{"title":"细胞外囊泡上的气孔传播细胞死亡","authors":"Alexandra Flemming","doi":"10.1038/s41577-025-01133-w","DOIUrl":null,"url":null,"abstract":"A study in Cell shows that gasdermin D pores can be transferred from cell to cell via extracellular vesicles and induce pyroptotic cell death in bystander cells.","PeriodicalId":19049,"journal":{"name":"Nature Reviews Immunology","volume":"118 1","pages":""},"PeriodicalIF":67.7000,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Gasdermin pores on extracellular vesicles spread cell death\",\"authors\":\"Alexandra Flemming\",\"doi\":\"10.1038/s41577-025-01133-w\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A study in Cell shows that gasdermin D pores can be transferred from cell to cell via extracellular vesicles and induce pyroptotic cell death in bystander cells.\",\"PeriodicalId\":19049,\"journal\":{\"name\":\"Nature Reviews Immunology\",\"volume\":\"118 1\",\"pages\":\"\"},\"PeriodicalIF\":67.7000,\"publicationDate\":\"2025-01-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature Reviews Immunology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1038/s41577-025-01133-w\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"IMMUNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Reviews Immunology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41577-025-01133-w","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
细胞》(Cell)杂志上的一项研究表明,气敏 D 孔可以通过细胞外囊泡从细胞转移到细胞,并诱导旁观细胞发生热猝死。
Gasdermin pores on extracellular vesicles spread cell death
A study in Cell shows that gasdermin D pores can be transferred from cell to cell via extracellular vesicles and induce pyroptotic cell death in bystander cells.
期刊介绍:
Nature Reviews Immunology is a journal that provides comprehensive coverage of all areas of immunology, including fundamental mechanisms and applied aspects. It has two international standard serial numbers (ISSN): 1474-1733 for print and 1474-1741 for online. In addition to review articles, the journal also features recent developments and new primary papers in the field, as well as reflections on influential people, papers, and events in the development of immunology. The subjects covered by Nature Reviews Immunology include allergy and asthma, autoimmunity, antigen processing and presentation, apoptosis and cell death, chemokines and chemokine receptors, cytokines and cytokine receptors, development and function of cells of the immune system, haematopoiesis, infection and immunity, immunotherapy, innate immunity, mucosal immunology and the microbiota, regulation of the immune response, signalling in the immune system, transplantation, tumour immunology and immunotherapy, and vaccine development.