急性脊髓损伤的外科和神经强化治疗:叙述性回顾。

Q3 Medicine
Korean Journal of Neurotrauma Pub Date : 2024-12-26 eCollection Date: 2024-12-01 DOI:10.13004/kjnt.2024.20.e44
Woo-Keun Kwon, Chang-Hwa Ham, Joonho Byun, Je Hoon Jeong, Myeong Jin Ko, Subum Lee, Byung-Jou Lee, Jong Hyun Kim
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引用次数: 0

摘要

高能创伤后的脊髓损伤通常会导致持久的神经功能缺损和严重的社会经济影响。有效的神经重症监护,特别是在损伤后的早期阶段,对优化结果至关重要。这篇综述讨论了神经重症监护在治疗脊髓损伤中的作用,强调了基于近期循证实践的早期评估、稳定和干预策略。脊髓损伤是由脊髓的原发性机械损伤引起的,引起涉及血管和细胞功能障碍的继发性损伤。早期神经重症监护的重点是稳定气道、呼吸和循环,同时防止进一步的脊柱损伤。影像学和神经学评估,包括ASIA量表,指导治疗计划。对于脊柱不稳定或脊髓受压的患者,广泛支持在24小时内进行早期减压手术。药理学策略旨在减少继发性损伤,尽管标准化仍然有限。预防深静脉血栓形成和肺栓塞,强化肺支持和监测压疮是早期脊髓损伤的关键。早期神经重症监护和外科干预在缓解脊髓损伤进展中起着关键作用。最佳护理需要多方面的方法来解决神经系统和全身并发症,这对康复和长期生活质量有重大影响。规范药物治疗和优化手术时机需要进一步的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Surgical and Neurointensive Management for Acute Spinal Cord Injury: A Narrative Review.

Spinal cord injury (SCI) following high-energy trauma often leads to lasting neurologic deficits and severe socioeconomic impact. Effective neurointensive care, particularly in the early stages post-injury, is essential for optimizing outcomes. This review discusses the role of neurointensive care in managing SCI, emphasizing early assessment, stabilization, and intervention strategies based on recent evidence-based practices. SCI results from primary mechanical damage to the spinal cord, triggering secondary injuries involving vascular and cellular dysfunction. Early neurointensive care focuses on stabilizing airway, breathing, and circulation while preventing further spinal damage. Imaging and neurologic assessments, including the ASIA scale, guide the management plan. Early decompressive surgery within 24 hours is widely supported for patients with spinal instability or cord compression. Pharmacologic strategies aim to reduce secondary injury, though standardization remains limited. Prophylaxis for deep vein thrombosis and pulmonary embolism, intensive pulmonary support, and monitoring for pressure sores are critical in early-phase SCI. Early neurointensive care and surgical interventions play a pivotal role in mitigating SCI progression. Optimal care requires a multifaceted approach addressing both neurologic and systemic complications, significantly influencing recovery and long-term quality of life. Further research is needed to standardize pharmacologic treatments and optimize surgical timing.

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CiteScore
1.10
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