{"title":"参芪注射液加益生菌改善胃癌部分切除术后患者的营养状况。","authors":"Yafeng Liu, Mingke Jia","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>In recent years, the incidence of gastric cancer (GC) has been on the rise, surgical procedures usually require the removal of part of gastric tissue connected with the tumor lesion, which leads to poor postoperative health and adverse prognosis in patients. Probiotics, as an active microorganism, play an important role in improving gastrointestinal function and enhancing immunity. In this study, we randomized 135 GC patients into a control group, a probiotic group and a combination group. All the study subjects were treated with radical GC resection in our hospital. Postoperatively, the control group was given routine treatment, the probiotic group received routine treatment + probiotics and the combined group was given routine treatment+ probiotics +Shenqi injection. Through research, we found that after the use of probiotics, the postoperative rehabilitation process of GC patients was significantly shortened compared to patients treated with conventional enteral nutrition suspension, the immune function and nutritional status were validly improved and the prognostic survival rate was increased. In addition, the CD4+, ALB, HGB, PA and TP of patients in the combination group were higher than those in the probiotic group (P<0.05), while CD4+/CD8+ were lower than those in the probiotic group (P<0.05).</p>","PeriodicalId":19971,"journal":{"name":"Pakistan journal of pharmaceutical sciences","volume":"37 6","pages":"1223-1228"},"PeriodicalIF":0.7000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Shenqi injection plus probiotics improves nutritional status in patients with gastric cancer after partial gastrectomy.\",\"authors\":\"Yafeng Liu, Mingke Jia\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In recent years, the incidence of gastric cancer (GC) has been on the rise, surgical procedures usually require the removal of part of gastric tissue connected with the tumor lesion, which leads to poor postoperative health and adverse prognosis in patients. Probiotics, as an active microorganism, play an important role in improving gastrointestinal function and enhancing immunity. In this study, we randomized 135 GC patients into a control group, a probiotic group and a combination group. All the study subjects were treated with radical GC resection in our hospital. Postoperatively, the control group was given routine treatment, the probiotic group received routine treatment + probiotics and the combined group was given routine treatment+ probiotics +Shenqi injection. Through research, we found that after the use of probiotics, the postoperative rehabilitation process of GC patients was significantly shortened compared to patients treated with conventional enteral nutrition suspension, the immune function and nutritional status were validly improved and the prognostic survival rate was increased. In addition, the CD4+, ALB, HGB, PA and TP of patients in the combination group were higher than those in the probiotic group (P<0.05), while CD4+/CD8+ were lower than those in the probiotic group (P<0.05).</p>\",\"PeriodicalId\":19971,\"journal\":{\"name\":\"Pakistan journal of pharmaceutical sciences\",\"volume\":\"37 6\",\"pages\":\"1223-1228\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2024-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pakistan journal of pharmaceutical sciences\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pakistan journal of pharmaceutical sciences","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
Shenqi injection plus probiotics improves nutritional status in patients with gastric cancer after partial gastrectomy.
In recent years, the incidence of gastric cancer (GC) has been on the rise, surgical procedures usually require the removal of part of gastric tissue connected with the tumor lesion, which leads to poor postoperative health and adverse prognosis in patients. Probiotics, as an active microorganism, play an important role in improving gastrointestinal function and enhancing immunity. In this study, we randomized 135 GC patients into a control group, a probiotic group and a combination group. All the study subjects were treated with radical GC resection in our hospital. Postoperatively, the control group was given routine treatment, the probiotic group received routine treatment + probiotics and the combined group was given routine treatment+ probiotics +Shenqi injection. Through research, we found that after the use of probiotics, the postoperative rehabilitation process of GC patients was significantly shortened compared to patients treated with conventional enteral nutrition suspension, the immune function and nutritional status were validly improved and the prognostic survival rate was increased. In addition, the CD4+, ALB, HGB, PA and TP of patients in the combination group were higher than those in the probiotic group (P<0.05), while CD4+/CD8+ were lower than those in the probiotic group (P<0.05).
期刊介绍:
Pakistan Journal of Pharmaceutical Sciences (PJPS) is a peer reviewed multi-disciplinary pharmaceutical sciences journal. The PJPS had its origin in 1988 from the Faculty of Pharmacy, University of Karachi as a biannual journal, frequency converted as quarterly in 2005, and now PJPS is being published as bi-monthly from January 2013.
PJPS covers Biological, Pharmaceutical and Medicinal Research (Drug Delivery, Pharmacy Management, Molecular Biology, Biochemical, Pharmacology, Pharmacokinetics, Phytochemical, Bio-analytical, Therapeutics, Biotechnology and research on nano particles.