意外危及生命的一餐：台湾被苯丙酸污染。

IF 2 4区医学 Q2 OBSTETRICS & GYNECOLOGY

Taiwanese Journal of Obstetrics & Gynecology Pub Date : 2025-01-01 DOI:10.1016/j.tjog.2024.10.003

Ching-Hsiang Yu , En-Chih Liao , Yu-Jang Su

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引用次数: 0

摘要

目的：BKA是一种与食源性疾病有关的危及生命的毒素。在此，我们报告于2024年3月，在台湾东台北，33名服用BKA的患者中，有2人死亡。病例报告：我们的第一个病例涉及一名40岁女性，她在食用湿米粉后出现恶心、呕吐和腹泻。经检查，出现难治性低血压、黄疸、弥漫性腹痛、高水平肝酶、代谢性酸中毒、凝血功能障碍和急性肝功能衰竭。透析、持续静脉-静脉血液滤过、血浆置换；然而，患者出现肝功能衰竭，并于第39天死于多器官功能衰竭、严重败血症和凝血功能障碍。第二个病例是一名39岁的男子，被发现失去意识并出现心脏骤停。在进入重症监护室后，经过30分钟的心肺复苏，他最终死亡。结论：应加强食品安全法规，加强对食品生产、储存和制备设施的检查，以防止与BKA中毒有关的死亡。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Unexpectedly life-threatening meal: Contamination by Bongkrekic acid in Taiwan

Objective

Bongkrekic acid (BKA) is a life-threatening toxin linked to foodborne illnesses. Herein, we report two fatalities among 33 patients who ingested BKA in March 2024, East Taipei, Taiwan.

Case Report

Our first case involved a 40-year-old female who presented with nausea, vomiting, and diarrhea after consuming wet rice noodles. On examination, refractory hypotension, jaundice, diffuse abdominal pain, high levels of liver enzymes, metabolic acidosis, coagulopathy, and acute hepatic failure were present. Dialysis, continuous venovenous hemofiltration, and plasma exchange were performed; however, the patient experienced liver failure and died of multi-organ failure, severe sepsis, and coagulopathy on day 39. The second case, a 39-year-old man, was found unconscious and experiencing cardiac arrest. He eventually died after 30 min of cardiopulmonary resuscitation following admission to the intensive care unit.

Conclusion

Strengthening food safety regulations by enhancing inspection of food production, storage, and preparation facilities should be implemented to prevent BKA poisoning-related fatalities.

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来源期刊

Taiwanese Journal of Obstetrics & Gynecology OBSTETRICS & GYNECOLOGY-

CiteScore

3.60

自引率

23.80%

发文量

207

审稿时长

4-8 weeks

期刊介绍： Taiwanese Journal of Obstetrics and Gynecology is a peer-reviewed journal and open access publishing editorials, reviews, original articles, short communications, case reports, research letters, correspondence and letters to the editor in the field of obstetrics and gynecology. The aims of the journal are to: 1.Publish cutting-edge, innovative and topical research that addresses screening, diagnosis, management and care in women''s health 2.Deliver evidence-based information 3.Promote the sharing of clinical experience 4.Address women-related health promotion The journal provides comprehensive coverage of topics in obstetrics & gynecology and women''s health including maternal-fetal medicine, reproductive endocrinology/infertility, and gynecologic oncology. Taiwan Association of Obstetrics and Gynecology.