扩大代谢功能障碍相关脂肪变性肝病和癌症的研究视野。

IF 11.4 1区医学 Q1 ENDOCRINOLOGY & METABOLISM

Trends in Endocrinology and Metabolism Pub Date : 2025-01-09 DOI:10.1016/j.tem.2024.12.009

Amedeo Lonardo, Norbert Stefan, Alessandro Mantovani

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引用次数: 0

摘要

在代谢功能障碍相关脂肪变性肝病（MASLD）的背景下，肝纤维化和生物性别可变地调节肝细胞癌（HCC）和肝外癌（EHCs）的风险。在这里，我们强调这些变量如何在MASLD的化学预防和精准医学方法的设置中产生影响，并指导进一步的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Widening research horizons on metabolic dysfunction-associated steatotic liver disease and cancer.

Liver fibrosis and biological sex variably modulate the risks of hepatocellular carcinoma (HCC) and extrahepatic cancers (EHCs) arising in the context of metabolic dysfunction-associated steatotic liver disease (MASLD). Here, we highlight how these variables may have implications in the setting of chemoprevention and precision medicine approaches in MASLD and guide additional research.

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来源期刊

Trends in Endocrinology and Metabolism 医学-内分泌学与代谢

CiteScore

20.10

自引率

0.00%

发文量

审稿时长

82 days

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