Christian Apfelbacher, Anthony Bewley, Sonja Molin, Maria Concetta Fargnoli, Ana Maria Giménez-Arnau, Lysel Brignoli, Bleuenn Rault, Jenny M Norlin, Tea Skaaby, Marie-Noëlle Crépy
{"title":"成人慢性手部湿疹的患病率:对加拿大、法国、德国、意大利、西班牙和英国6万多名普通人群的横断面调查。","authors":"Christian Apfelbacher, Anthony Bewley, Sonja Molin, Maria Concetta Fargnoli, Ana Maria Giménez-Arnau, Lysel Brignoli, Bleuenn Rault, Jenny M Norlin, Tea Skaaby, Marie-Noëlle Crépy","doi":"10.1093/bjd/ljaf020","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The lack of attention paid to chronic hand eczema (CHE) and the lack of a specific International Classification of Diseases code for it may have limited assessment of its prevalence. To date, prevalence estimates have primarily been derived from (partly small) single-country studies.</p><p><strong>Objectives: </strong>To estimate the annual prevalence of self-reported physician-diagnosed CHE across sociodemographic characteristics in adults living in Canada, France, Germany, Italy, Spain and the UK.</p><p><strong>Methods: </strong>In the observational Chronic Hand Eczema epidemiology, Care, and Knowledge of real-life burden (CHECK) study, a questionnaire was administered to adults aged 18-69 years in the general population, recruited through online panels. Quotas and minor weighting adjustments were performed to ensure that the participants were representative of the general population with regard to sex, age, region, employment status, urban/rural setting and - in the UK only - ethnicity. Additional weights were applied to account for population size differences when aggregating country results. Information on self-reported physician-diagnosed CHE was collected. CHE was defined, in accordance with the European Society of Contact Dermatitis, as having had hand eczema continuously for ≥ 3 months or at least two flares in the past 12 months. The annual prevalence of CHE was determined for each country, and by subgroups of sex, age, employment and urban/rural setting.</p><p><strong>Results: </strong>Of 60 131 participants, 2847 self-reported physician-diagnosed CHE, yielding an annual prevalence of 4.7% [95% confidence interval (CI) 4.6-4.9]. Subgroup analyses revealed that the prevalence of CHE was significantly higher in women than in men [5.6% (95% CI 5.4-5.9) vs. 3.8% (95% CI 3.6-4.1); P < 0.001], in employed vs. unemployed people [5.3% (95% CI 5.1-5.6) vs. 3.3% (95% CI 3.1-3.6); P < 0.001] and in urban vs. rural residents [5.0% (95% CI 4.8-5.2) vs. 3.7% (95% CI 3.4-4.1); P < 0.001). Prevalence was highest in those aged 30-39 years (6.5%, 95% CI 6.0-7.0) and lowest in those aged 60-69 years (2.6%, 95% CI 2.3-3.0).</p><p><strong>Conclusions: </strong>This large multinational study is the first to assess the prevalence of CHE in Europe and Canada using a consistent definition across a broad geographical population. This study reveals that CHE is a common skin disease with annual prevalence of 4.7%, with a higher prevalence in women, people aged 30-39, employed people and those living in urban areas.</p>","PeriodicalId":9238,"journal":{"name":"British Journal of Dermatology","volume":" ","pages":"1047-1054"},"PeriodicalIF":11.0000,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prevalence of chronic hand eczema in adults: a cross-sectional survey of over 60 000 respondents from the general population of Canada, France, Germany, Italy, Spain and the UK.\",\"authors\":\"Christian Apfelbacher, Anthony Bewley, Sonja Molin, Maria Concetta Fargnoli, Ana Maria Giménez-Arnau, Lysel Brignoli, Bleuenn Rault, Jenny M Norlin, Tea Skaaby, Marie-Noëlle Crépy\",\"doi\":\"10.1093/bjd/ljaf020\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>The lack of attention paid to chronic hand eczema (CHE) and the lack of a specific International Classification of Diseases code for it may have limited assessment of its prevalence. To date, prevalence estimates have primarily been derived from (partly small) single-country studies.</p><p><strong>Objectives: </strong>To estimate the annual prevalence of self-reported physician-diagnosed CHE across sociodemographic characteristics in adults living in Canada, France, Germany, Italy, Spain and the UK.</p><p><strong>Methods: </strong>In the observational Chronic Hand Eczema epidemiology, Care, and Knowledge of real-life burden (CHECK) study, a questionnaire was administered to adults aged 18-69 years in the general population, recruited through online panels. Quotas and minor weighting adjustments were performed to ensure that the participants were representative of the general population with regard to sex, age, region, employment status, urban/rural setting and - in the UK only - ethnicity. Additional weights were applied to account for population size differences when aggregating country results. Information on self-reported physician-diagnosed CHE was collected. CHE was defined, in accordance with the European Society of Contact Dermatitis, as having had hand eczema continuously for ≥ 3 months or at least two flares in the past 12 months. The annual prevalence of CHE was determined for each country, and by subgroups of sex, age, employment and urban/rural setting.</p><p><strong>Results: </strong>Of 60 131 participants, 2847 self-reported physician-diagnosed CHE, yielding an annual prevalence of 4.7% [95% confidence interval (CI) 4.6-4.9]. Subgroup analyses revealed that the prevalence of CHE was significantly higher in women than in men [5.6% (95% CI 5.4-5.9) vs. 3.8% (95% CI 3.6-4.1); P < 0.001], in employed vs. unemployed people [5.3% (95% CI 5.1-5.6) vs. 3.3% (95% CI 3.1-3.6); P < 0.001] and in urban vs. rural residents [5.0% (95% CI 4.8-5.2) vs. 3.7% (95% CI 3.4-4.1); P < 0.001). Prevalence was highest in those aged 30-39 years (6.5%, 95% CI 6.0-7.0) and lowest in those aged 60-69 years (2.6%, 95% CI 2.3-3.0).</p><p><strong>Conclusions: </strong>This large multinational study is the first to assess the prevalence of CHE in Europe and Canada using a consistent definition across a broad geographical population. This study reveals that CHE is a common skin disease with annual prevalence of 4.7%, with a higher prevalence in women, people aged 30-39, employed people and those living in urban areas.</p>\",\"PeriodicalId\":9238,\"journal\":{\"name\":\"British Journal of Dermatology\",\"volume\":\" \",\"pages\":\"1047-1054\"},\"PeriodicalIF\":11.0000,\"publicationDate\":\"2025-05-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"British Journal of Dermatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1093/bjd/ljaf020\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"British Journal of Dermatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/bjd/ljaf020","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DERMATOLOGY","Score":null,"Total":0}
Prevalence of chronic hand eczema in adults: a cross-sectional survey of over 60 000 respondents from the general population of Canada, France, Germany, Italy, Spain and the UK.
Background: The lack of attention paid to chronic hand eczema (CHE) and the lack of a specific International Classification of Diseases code for it may have limited assessment of its prevalence. To date, prevalence estimates have primarily been derived from (partly small) single-country studies.
Objectives: To estimate the annual prevalence of self-reported physician-diagnosed CHE across sociodemographic characteristics in adults living in Canada, France, Germany, Italy, Spain and the UK.
Methods: In the observational Chronic Hand Eczema epidemiology, Care, and Knowledge of real-life burden (CHECK) study, a questionnaire was administered to adults aged 18-69 years in the general population, recruited through online panels. Quotas and minor weighting adjustments were performed to ensure that the participants were representative of the general population with regard to sex, age, region, employment status, urban/rural setting and - in the UK only - ethnicity. Additional weights were applied to account for population size differences when aggregating country results. Information on self-reported physician-diagnosed CHE was collected. CHE was defined, in accordance with the European Society of Contact Dermatitis, as having had hand eczema continuously for ≥ 3 months or at least two flares in the past 12 months. The annual prevalence of CHE was determined for each country, and by subgroups of sex, age, employment and urban/rural setting.
Results: Of 60 131 participants, 2847 self-reported physician-diagnosed CHE, yielding an annual prevalence of 4.7% [95% confidence interval (CI) 4.6-4.9]. Subgroup analyses revealed that the prevalence of CHE was significantly higher in women than in men [5.6% (95% CI 5.4-5.9) vs. 3.8% (95% CI 3.6-4.1); P < 0.001], in employed vs. unemployed people [5.3% (95% CI 5.1-5.6) vs. 3.3% (95% CI 3.1-3.6); P < 0.001] and in urban vs. rural residents [5.0% (95% CI 4.8-5.2) vs. 3.7% (95% CI 3.4-4.1); P < 0.001). Prevalence was highest in those aged 30-39 years (6.5%, 95% CI 6.0-7.0) and lowest in those aged 60-69 years (2.6%, 95% CI 2.3-3.0).
Conclusions: This large multinational study is the first to assess the prevalence of CHE in Europe and Canada using a consistent definition across a broad geographical population. This study reveals that CHE is a common skin disease with annual prevalence of 4.7%, with a higher prevalence in women, people aged 30-39, employed people and those living in urban areas.
期刊介绍:
The British Journal of Dermatology (BJD) is committed to publishing the highest quality dermatological research. Through its publications, the journal seeks to advance the understanding, management, and treatment of skin diseases, ultimately aiming to improve patient outcomes.