戊糖途径形成所有必需代谢物的能力为新陈代谢的起源提供了线索。

IF 9.8 1区生物学 Q1 Agricultural and Biological Sciences

PLoS Biology Pub Date : 2025-01-10 eCollection Date: 2025-01-01 DOI:10.1371/journal.pbio.3002996

Steffen N Lindner, Markus Ralser

引用次数: 0

摘要

早期代谢网络的结构尚不清楚。在这里，我们报告说，当考虑在一起，戊糖利用途径形成所有生命必需的前体。因此，我们推测在戊糖代谢中保存的化学物质可能是早期代谢的中心结构元素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The ability of pentose pathways to form all essential metabolites provides clues to the origins of metabolism.

The structure of the early metabolic network is unknown. Here, we report that when considered together, pentose utilization pathways form all life-essential precursors. We speculate that the chemistry preserved in pentose metabolism could therefore have been a central structural element in early metabolism.

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来源期刊

PLoS Biology BIOCHEMISTRY & MOLECULAR BIOLOGY-BIOLOGY

CiteScore

15.40

自引率

2.00%

发文量

359

审稿时长

3-8 weeks

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