男性下尿路症状的自我管理干预：随机对照试验的系统回顾和荟萃分析

IF 3.5 3区医学 Q2 GERIATRICS & GERONTOLOGY

Archives of gerontology and geriatrics Pub Date : 2024-12-31 DOI:10.1016/j.archger.2024.105742

Akash Kumar , Hamza Ashraf , Priyanka Keshav Lal , Rubyisha Sheikh , Shanzay Akhtar , Ahsan Raza Raja , Ibrahim Nagm , Ram , Haider Ashfaq

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引用次数: 0

摘要

下尿路症状（LUTS）显著影响男性的生活质量，并可引起令人烦恼的症状，这些症状往往干扰日常功能并导致心理困扰。虽然药物和手术治疗是有效的，但它们可能有副作用，并不是所有的男性都需要或希望这些干预措施。本研究的目的是评估自我管理干预对症状严重程度的影响。方法：我们对多个数据库进行了系统检索，包括PubMed、Embase和Cochrane Library，检索时间从成立到2024年8月。我们确定了评估男性LUTS自我管理干预的随机对照试验（rct）。评估研究的质量，并分析BPH影响指数、国际前列腺症状评分（IPSS）和生活质量的结果。通过LFK指数、敏感性分析和Doi图检验发表偏倚和异质性。结果：自我管理显著降低3个月BPH影响指数(SMD: -0.73；p = 0.0003)和6个月(SMD: -0.95；P = 0.05)，但存在发表偏倚。IPSS在3个月时显著下降(MD: -5.52；p < 0.01)， 6个月(MD: -5.50；p = 0.002)， 12个月(MD: -3.51；P = 0.01)。6个月和12个月的生活质量也有所改善（SMD: -0.34, p = 0.002, SMD: -0.30, p < 0.01）。在调整研究异质性后，敏感性分析证实了这些发现的一致性。结论：我们的研究结果表明，自我管理干预在降低LUTS严重程度和提高男性生活质量方面提供了显著的益处。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Self-management interventions for men with lower urinary tract symptoms: A systematic review and meta-analysis of randomized controlled trials

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Self-management interventions for men with lower urinary tract symptoms: A systematic review and meta-analysis of randomized controlled trials

Introduction

Lower urinary tract symptoms (LUTS) significantly impact men's quality of life and can cause bothersome symptoms, which often interfere with daily functioning and contribute to psychological distress. While pharmacological and surgical treatments are effective, they can have side effects, and not all men require or desire these interventions. The aim of this study is to assess the impact of self-management interventions on symptom severity.

Methods

We conducted a systematic search across multiple databases, including PubMed, Embase, and Cochrane Library, from inception to August 2024. We identified randomized controlled trials (RCTs) assessing self-management interventions for LUTS in men. Studies were evaluated for quality and analyzed for outcomes on BPH Impact Index, International Prostate Symptom Score (IPSS), and QoL. Publication bias and heterogeneity were examined through LFK indices, sensitivity analyses, and Doi plots.

Results

Self-management significantly reduced the BPH Impact Index at 3 months (SMD: -0.73; p = 0.0003) and 6 months (SMD: -0.95; p = 0.05), though publication bias was indicated. The IPSS decreased significantly at 3 months (MD: -5.52; p < 0.01), 6 months (MD: -5.50; p = 0.002), and 12 months (MD: -3.51; p = 0.01). Quality of life also improved at 6 and 12 months (SMD: -0.34, p = 0.002, and SMD: -0.30, p < 0.01, respectively). Sensitivity analysis confirmed the consistency of these findings after adjusting for study heterogeneity.

Conclusion

Our findings suggest that self-management interventions provide a significant benefit in reducing LUTS severity and enhancing quality of life in men.

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来源期刊

Archives of gerontology and geriatrics 医学-老年医学

CiteScore

7.30

自引率

5.00%

发文量

198

审稿时长

16 days

期刊介绍： Archives of Gerontology and Geriatrics provides a medium for the publication of papers from the fields of experimental gerontology and clinical and social geriatrics. The principal aim of the journal is to facilitate the exchange of information between specialists in these three fields of gerontological research. Experimental papers dealing with the basic mechanisms of aging at molecular, cellular, tissue or organ levels will be published. Clinical papers will be accepted if they provide sufficiently new information or are of fundamental importance for the knowledge of human aging. Purely descriptive clinical papers will be accepted only if the results permit further interpretation. Papers dealing with anti-aging pharmacological preparations in humans are welcome. Papers on the social aspects of geriatrics will be accepted if they are of general interest regarding the epidemiology of aging and the efficiency and working methods of the social organizations for the health care of the elderly.