哥斯达黎加老年人的社会关系、白细胞端粒长度和全因死亡率:哥斯达黎加长寿和健康老龄化研究(CRELES)。

IF 2.2 3区 医学 Q2 GERONTOLOGY
Danting Gan, Ana Baylin, Karen E Peterson, Luis Rosero-Bixby, Edward A Ruiz-Narváez
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引用次数: 0

摘要

目的:研究哥斯达黎加老年人血液白细胞端粒长度(LTL)和全因死亡率与社会关系的关系。方法:利用哥斯达黎加长寿与健康老龄化研究(CRELES)的数据,自2004年以来跟踪了2827名60岁及以上的个体,我们基于婚姻状况、家庭规模、与非同居成年子女的互动以及教会出席率构建了社会网络指数(SNI)。我们使用线性回归来评估SNI与基线LTL的关系(N = 1113),并使用Cox比例风险模型来检验SNI与全因死亡率的关系(N = 2735)。结果:SNI水平越高,端粒越长,随访期间全因死亡率降低。结婚和定期去教堂分别使全因死亡率降低23%和24%。讨论:这些发现强调了促进哥斯达黎加老年人长寿的社会参与的重要性,这对全球老龄化人口提出了更广泛的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Social Connections, Leukocyte Telomere Length, and All-Cause Mortality in Older Adults From Costa Rica: The Costa Rican Longevity and Healthy Aging Study (CRELES).

Objectives: To examine the association of social connections with blood leukocyte telomere length (LTL) and all-cause mortality in older Costa Ricans.

Methods: Utilizing data from the Costa Rican Longevity and Healthy Aging Study (CRELES), a prospective cohort of 2827 individuals aged 60 and above followed since 2004, we constructed a Social Network Index (SNI) based on marital status, household size, interaction with non-cohabitating adult children, and church attendance. We used linear regression to assess SNI's association with baseline LTL (N = 1113), and Cox proportional-hazard models to examine SNI's relationship with all-cause mortality (N = 2735).

Results: Higher SNI levels were associated with longer telomeres and decreased all-cause mortality during follow-up. Being married and regular church attendance were associated with 23% and 24% reductions of the all-cause mortality, respectively.

Discussion: These findings underscore the importance of social engagement in promoting longevity among older Costa Ricans, suggesting broader implications for aging populations globally.

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来源期刊
CiteScore
5.60
自引率
3.60%
发文量
113
期刊介绍: The Journal of Aging and Health is an interdisciplinary forum for the presentation of research findings and scholarly exchange in the area of aging and health. Manuscripts are sought that deal with social and behavioral factors related to health and aging. Disciplines represented include the behavioral and social sciences, public health, epidemiology, demography, health services research, nursing, social work, medicine, and related disciplines. Although preference is given to manuscripts presenting the findings of original research, review and methodological pieces will also be considered.
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