微生物简介：鼠伤寒沙门氏菌：适应艺术的大师。

IF 2.6 4区生物学 Q3 MICROBIOLOGY

Microbiology-Sgm Pub Date : 2025-01-01 DOI:10.1099/mic.0.001521

Blanca M Perez-Sepulveda, Jay C D Hinton

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引用次数: 0

摘要

鼠伤寒沙门氏菌是一种主要的沙门氏菌血清型，在全球都有发现。它对与食品生产工业化广泛相关的自限性肠胃炎的暴发负有责任。鼠伤寒沙门氏菌是一种宿主范围广、代谢多样性显著的病原体。约5mb的基因组包括pSLT毒力质粒，并具有特征性的前噬菌体库。主要的毒力决定因子由多种致病性岛编码。正在出现的多药耐药鼠伤寒沙门氏菌流行谱系目前正在撒哈拉以南非洲造成血液感染。鼠伤寒沙门氏菌的多功能性和适应性构成了一个重要的公共卫生挑战。

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Microbe Profile: Salmonella Typhimurium: the master of the art of adaptation.

Salmonella Typhimurium is a major Salmonella serovar that is found globally. It is responsible for outbreaks of self-limiting gastroenteritis that are broadly linked to the industrialization of food production. S. Typhimurium is a pathogen with a broad host range and remarkable metabolic versatility. The ∼5 Mb genome includes the pSLT virulence plasmid and has a characteristic prophage repertoire. The major virulence determinants are encoded by a variety of pathogenicity islands. Emerging multidrug-resistant lineages of epidemics of S. Typhimurium are currently causing bloodstream infections in sub-Saharan Africa. The versatility and adaptability of S. Typhimurium pose an important public health challenge.

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来源期刊

Microbiology-Sgm 生物-微生物学

CiteScore

4.60

自引率

7.10%

发文量

132

审稿时长

3.0 months

期刊介绍： We publish high-quality original research on bacteria, fungi, protists, archaea, algae, parasites and other microscopic life forms. Topics include but are not limited to: Antimicrobials and antimicrobial resistance Bacteriology and parasitology Biochemistry and biophysics Biofilms and biological systems Biotechnology and bioremediation Cell biology and signalling Chemical biology Cross-disciplinary work Ecology and environmental microbiology Food microbiology Genetics Host–microbe interactions Microbial methods and techniques Microscopy and imaging Omics, including genomics, proteomics and metabolomics Physiology and metabolism Systems biology and synthetic biology The microbiome.