David F. Lehmann PharmD, MD, Aryana Nazem BS, Jeanna Marraffa PharmD, MPH, DABAT, FAACT, Ramsay Sami Farah MD
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Street Pharmacology: Toxico-Dermatology of Injection Drug Use
Street medicine is a point-of-care, mobile approach that services the needs of unhoused individuals who are otherwise unable to access medical care in traditional settings. The prevalence of injection drug use combines with the pipeline of illicit substances, to produce a constellation of severe, potentially life-threatening dermatological disorders unique to this population. This review applies principles of clinical pharmacology to clarify the mechanisms underlying the dermatological toxicity of xylazine, desomorphine, and 3,4-methylenedioxymethamphetamine (MDMA).
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