The Journal of Clinical Pharmacology

Influence of Disease Type and Activity on Adalimumab Exposure in Children with Inflammatory Rheumatic Diseases

Pub Date : 2025-05-23 DOI: 10.1002/jcph.70045 Klervi Golhen PharmD, PhD, Tatjana Welzel MD, Andrew Atkinson PhD, Gilbert Koch PhD, Dominic Braem PhD, Johannes van den Anker MD, PhD, Andreas Woerner MD, Marc Pfister MD, Verena Gotta PhD

Population Pharmacokinetics and Exposure–Response Relationships of Etrolizumab in Patients with Moderately-to-Severely Active Crohn's Disease

Pub Date : 2025-05-22 DOI: 10.1002/jcph.70043 Anita Moein PhD, Jakob Ribbing PhD, Moustafa M. A. Ibrahim PhD, Wenhui Zhang PhD, Nastya Kassir PharmD, PhD

Comparison of Analysis of Covariance and Analysis of Variance in Pharmacokinetic Similarity Studies

Pub Date : 2025-05-19 DOI: 10.1002/jcph.70041 Brett A. Martini MPH, Ping Ji PhD, Jiang Liu PhD, Jan-Shiang Taur PhD, Jianmeng Chen PhD, MD, Suresh Doddapaneni PhD, Chandrahas Sahajwalla PhD, Sarah J. Schrieber PharmD