The Journal of Clinical Pharmacology

Pain Severity Trajectories and Patient Profiles in Chronic Pain Patients Treated with Cannabis-Based Medicinal Products: A k-Means Clustering Analysis of the UK Medical Cannabis Registry

Pub Date : 2026-10-16 DOI: 10.1002/jcph.70313 Simon Erridge MBBS, BSc, Aritra Datta MBBS, BSc, Aditya Mukherjee MBBS, BSc, Dhruv Vasooja MBBS, BSc, Ross Coomber BSc, FRCS, Sushil Beri MD, MRCPCH, Shaheen A. Khan MSc, MRCP, Mark W. Weatherall PhD, FRCP, Michael W. Platt MA, FRCA, FFPM, RCA, James J. Rucker PhD, MRCPsych, Pedro A. M. Mediano MSc, PhD, Mikael H. Sodergren PhD, FRCS

Concentration-QTc Analysis Supporting Thorough QT Study Waiver for Forvisirvat: Electrocardiogram Assay Sensitivity Demonstrated via Meal Effect

Pub Date : 2026-10-15 DOI: 10.1002/jcph.70312 Yushi Kashihara PhD, Yoshiyuki Igawa PhD, Kei Okita MSc, Masaki Sasaki MSc, Takaki Ohara BSc, Masakatsu Kotsuma PhD, Kazutaka Yoshihara PhD

Mechanistic Prediction of Maternal, Fetal, and Amniotic Fluid Betamethasone Concentrations to Support Dosing Optimization in Pregnancy

Pub Date : 2026-10-14 DOI: 10.1002/jcph.70308 Alaa Mahdi MSc, Khaled Abduljalil PhD, Fernanda de Lima Moreira PhD, Hiral Raju Mehta PharmD, Jhohann Richard de Lima Benzi MSc, PhD, Alessandra Cristina Marcolin MD, MSc, PhD, Stephan Schmidt PhD, FCP, Natalia V. de Moraes PhD