The Journal of Clinical Pharmacology

In Vitro and Clinical Evaluations of UGT1A1-, P-gp-, OATP1B1-, and BCRP-Mediated Drug–Drug Interactions of Belumosudil, a Potent ROCK2 Inhibitor

Pub Date : 2025-03-27 DOI: 10.1002/jcph.70018 Olivier Schueller PhD, Lauren Lohmer PhD, Felix Beck MSc, Jeegar Patel PhD, Jasminder Sahi PhD

Once- Versus Twice-Daily Tacrolimus Therapy: Does Improved Adherence Lead to Better Efficacy?—A Pharmacokinetic Perspective

Pub Date : 2025-03-27 DOI: 10.1002/jcph.70021 Zi-yan Dai BSc, Lu Han BSc, Juan Wang BSc, Xiao-qin Liu PhD, Rui Chen PhD, Zheng Jiao PhD

Efanesoctocog Alfa Population Pharmacokinetics and Repeated Time-To-Event Analysis of Bleeds in Adults, Adolescents, and Children with Severe Hemophilia A

Pub Date : 2025-03-23 DOI: 10.1002/jcph.70008 Nancy Wong PhD, Pratik Bhagunde PhD, Joakim Nyberg PhD, Suresh Katragadda PhD, Marek Demissie MD, PhD, Annemieke Willemze MD, Craig Benson MD, Sreeraj Macha PhD