鼻中隔成形术改善鼻通畅和肺功能：一项前瞻性研究。

IF 1.6 4区医学 Q2 OTORHINOLARYNGOLOGY

Laryngoscope Investigative Otolaryngology Pub Date : 2025-01-07 DOI:10.1002/lio2.70065

Francisco Alves de Sousa MD, João Tavares Correia MD, João Carvalho Almeida MD, Sara Raquel Azevedo MD, Miguel Gonçalves Ferreira MD, PhD, Manuel Magalhães MD, PhD, Mariline Santos MD, PhD

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引用次数: 0

摘要

背景和目的：假设鼻中隔成形术和鼻甲复位手术（STR）通过改变气道动力学来影响肺功能。本研究探讨str介导的鼻通畅改善对肺功能测试（PFTs）的影响。方法：在前瞻性分析中，纳入了37例接受STR治疗的成年患者。术前、术后分别测量峰值鼻吸气流量（PNIF）和PFT参数，包括用力肺活量的25% （FEF25）和75% （FEF75）时的用力呼气流量以及肺容积的25- 75%之间的用力呼气流量（FEF25-75）、用力肺活量（FVC）和1秒用力呼气量（FEV1）。结果：PNIF （p p p）显著改善。结论：通过STR改善鼻腔通畅可影响下气道阻力，对鼻塞患者有潜在益处。观察到的∆PNIF和∆PFT之间的正相关关系值得进一步研究其潜在机制。证据等级：三级。

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Septoplasty-mediated improvements in nasal patency and pulmonary function: A prospective study

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Septoplasty-mediated improvements in nasal patency and pulmonary function: A prospective study

Background and Objective

Septoplasty and turbinate reduction surgery (STR) is hypothesized to affect pulmonary function by modifying airway dynamics. This study investigates the impact of STR-mediated improvements in nasal patency on pulmonary function tests (PFTs).

Methods

In a prospective analysis, 37 adult patients undergoing STR were enrolled. Peak nasal inspiratory flow (PNIF) and PFT parameters, including forced expiratory flow at 25% (FEF25) and 75% of forced vital capacity (FEF75) and forced expiratory flow between 25 and 75% of the pulmonary volume (FEF25–75), forced vital capacity (FVC), and forced expiratory volume in one second (FEV1), were measured before and after surgery.

Results

Significant improvements were observed in PNIF (p < .001). Additionally, significant improvements in peripheral airway function occurred, as measured by FEF25, FEF25-75, and FEF75 (p < .05), suggesting reduced airway resistance after STR. Notably, a significant positive correlation was found between the change in PNIF (∆PNIF) and the change in various PFT measurements (∆PFT) (p < .05). FVC and FEV1 did not show significant changes.

Conclusions

These findings suggest that improving nasal patency through STR can affect lower airway resistance, potentially benefiting patients with nasal obstruction. The observed positive correlation between ∆PNIF and ∆PFT warrants further investigation into the underlying mechanism.