儿童结核病——治疗和预防的进展。

IF 2.7 3区医学 Q1 PEDIATRICS

Pediatric Pulmonology Pub Date : 2025-01-07 DOI:10.1002/ppul.27375

Sandra Kwarteng Owusu

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引用次数: 0

摘要

儿童结核病是一项重大的全球负担，每年有近200万例儿童和青少年患病。大多数死于结核病的儿童从未得到适当的治疗。儿童结核病治疗进展缓慢，儿童结核病治疗面临许多挑战。然而，最近又重新努力为儿童提供更好的结核病治疗方案。非严重结核病的治疗时间缩短（4个月）和耐多药结核病的全口服治疗是儿童结核病治疗的主要标志。虽然卡介苗仍然是预防结核病的唯一疫苗，但也有针对婴儿和青少年的候选疫苗。

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Childhood Tuberculosis-Advances in Treatment and Prevention.

Tuberculosis (TB) in childhood presents a substantial global burden with nearly two million episodes of disease in children and adolescents annually. The majority of children who die from TB never receive appropriate treatment. Advancements in childhood TB treatments have been slow and there are many challenges with TB treatment in children. However, recently, there have been renewed efforts toward better options for TB treatment in children. The shortened duration of treatment (4 months) in nonsevere TB and an all-oral treatment for multidrug-resistant TB are major landmarks in childhood TB treatment. Although BCG remains the only vaccine for TB prevention, there are candidate vaccines that target infants and adolescents.

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来源期刊

Pediatric Pulmonology 医学-呼吸系统

CiteScore

6.00

自引率

12.90%

发文量

468

审稿时长

3-8 weeks

期刊介绍： Pediatric Pulmonology (PPUL) is the foremost global journal studying the respiratory system in disease and in health as it develops from intrauterine life though adolescence to adulthood. Combining explicit and informative analysis of clinical as well as basic scientific research, PPUL provides a look at the many facets of respiratory system disorders in infants and children, ranging from pathological anatomy, developmental issues, and pathophysiology to infectious disease, asthma, cystic fibrosis, and airborne toxins. Focused attention is given to the reporting of diagnostic and therapeutic methods for neonates, preschool children, and adolescents, the enduring effects of childhood respiratory diseases, and newly described infectious diseases. PPUL concentrates on subject matters of crucial interest to specialists preparing for the Pediatric Subspecialty Examinations in the United States and other countries. With its attentive coverage and extensive clinical data, this journal is a principle source for pediatricians in practice and in training and a must have for all pediatric pulmonologists.