血浆微生物无细胞DNA测序诊断儿童莱姆病。

IF 2.9 4区医学 Q3 IMMUNOLOGY

Pediatric Infectious Disease Journal Pub Date : 2024-12-31 DOI:10.1097/INF.0000000000004707

Andrew S Handel, Asim A Ahmed, Shivkumar Venkatasubrahmanyam, Sivan Bercovici, Qing Mao, Carine Ho, Desiree D Hollemon, Christy Beneri

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引用次数: 0

摘要

我们对血浆微生物无细胞DNA测序在儿科莱姆病诊断中的应用进行了探索性研究。低水平的伯氏疏螺旋体微生物无细胞DNA (

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Plasma Microbial Cell-Free DNA Sequencing for Diagnosis of Pediatric Lyme Disease.

We conducted an exploratory study of plasma microbial cell-free DNA sequencing for the diagnosis of Lyme disease among pediatric patients. Low levels of Borrelia burgdorferi microbial cell-free DNA (<3-5 molecules per microliter) were observed in 6/9 serologically confirmed participants, including 4/5 with arthritis and 2/3 with multiple erythema migrans.

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来源期刊

Pediatric Infectious Disease Journal 医学-传染病学

CiteScore

6.30

自引率

2.80%

发文量

566

审稿时长

2-4 weeks

期刊介绍： The Pediatric Infectious Disease Journal® (PIDJ) is a complete, up-to-the-minute resource on infectious diseases in children. Through a mix of original studies, informative review articles, and unique case reports, PIDJ delivers the latest insights on combating disease in children — from state-of-the-art diagnostic techniques to the most effective drug therapies and other treatment protocols. It is a resource that can improve patient care and stimulate your personal research.