单中心随机研究:预测模型是判断肾脏过度活动的可靠指标。

IF 2.9 2区 医学 Q1 UROLOGY & NEPHROLOGY
Çağri Doğan, Cihan Özgür, Mehmet Fatih Sahin, Duygu Sıddıkoglu, Erdem Can Topkaç, Cenk Murat Yazici
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引用次数: 0

摘要

目的:在逆行肾内手术(RIRS)和体外冲击波碎石术(ESL)中,过度的肾脏活动是一个被低估的挑战。目前还没有一种技术被批准为减少肾脏过度活动的金标准程序。该研究旨在通过利用临床人口学特征和非对比计算机断层扫描(NCCT)数据揭示确定肾脏过度活动的预测因素。材料与方法:根据患者是否存在肾活动过度分为两组。患者采用16通道多层NCCT扫描,图像采集采用16 × 1.25 mm准直,5 mm层厚。在图像上测量肾动脉起始角、肾动脉起始角、静脉长度、静脉直径、腰肌面积和长度、肾周和肾旁脂肪组织等参数并进行分析。数据分析采用多元logistic回归,采用受试者工作特征曲线模型,并采用基于三个显著参数的预测模型。结果:在2023年5月至2024年5月期间,共有140例有或无过度肾活动的患者入组研究。多因素分析显示,肾静脉长度和肾动脉起始角的增加可提高肾运动性(优势比[OR]: 0.982;95%置信区间[CI]: 0.966 ~ 0.998;p = 0.030, OR: 0.973;95% ci: 0.948-0.999;P = 0.044;分别)。研究还发现,潮气量增加导致肾脏活动性降低(OR: 1.015;95% ci: 1.007-1.024;P = 0.001)。根据这些结果设计预测模型。该预测模型准确地估计了肾脏过度活动的存在,提高了59%的特异性和65%的敏感性(p < 0.001,曲线下面积0.757;置信区间:0.671—-0.843)。结论:医生可以通过本文中提到的预测模型来预测肾脏过度活动的存在。他们可能会在ESL和RIRS之前进行操作以减少肾脏活动。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Predictive Modeling Is a Reliable Indicator in Determining Excessive Renal Mobility Single-Center Randomized Study.

Purpose: Excessive kidney mobility is an underestimating challenge for surgeons during retrograde intrarenal surgery (RIRS) and extracorporeal shock wave lithotripsy (ESL). There is no technique approved as a gold standard procedure for reducing excessive kidney mobility. The study aimed to uncover predictive factors for determining excessive renal mobility by utilizing clinicodemographic characteristics and noncontrast computed tomography (NCCT) data. Materials and Methods: The patients were categorized into two groups based on the presence of excessive renal mobility. Patients were scanned with a 16-channel, multislice NCCT, and images were captured utilizing a 16 × 1.25 mm collimation, 5 mm slice thickness. Many parameters including the origin angle of the renal artery, renal artery, vein length, diameter, the area and length of the psoas muscle, and perirenal and pararenal fatty tissue were measured on the images and analyzed. The data were analyzed using multivariate logistic regression, and the receiver operating characteristic curve model and we used predictive modeling based on three significant parameters. Results: Between May 2023 and May 2024, a total of 140 patients with and without excessive renal mobility enrolled into study. After multivariate analysis, increasing renal vein length and renal artery origin angle results in higher renal motility (odds ratio [OR]: 0.982; 95% confidence interval [CI]: 0.966-0.998; p = 0.030 and OR: 0.973; 95% CI: 0.948-0.999; p = 0.044; respectively). It also observed that an increase in tidal volume led to a reduction in renal mobility (OR: 1.015; 95% CI: 1.007-1.024; p = 0.001). Predictive modeling was designed based on these outcomes. This predictive modeling accurately estimates the presence of excessive renal mobility with improved 59% specificity and 65% sensitivity (p < 0.001, area under the curve 0.757; CI: 0.671-0.843). Conclusion: Physicians may predict the presence of excessive renal mobility via the predictive modeling mentioned in the current article. They may perform manipulations to reduce kidney mobility prior to ESL and RIRS.

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来源期刊
Journal of endourology
Journal of endourology 医学-泌尿学与肾脏学
CiteScore
5.50
自引率
14.80%
发文量
254
审稿时长
1 months
期刊介绍: Journal of Endourology, JE Case Reports, and Videourology are the leading peer-reviewed journal, case reports publication, and innovative videojournal companion covering all aspects of minimally invasive urology research, applications, and clinical outcomes. The leading journal of minimally invasive urology for over 30 years, Journal of Endourology is the essential publication for practicing surgeons who want to keep up with the latest surgical technologies in endoscopic, laparoscopic, robotic, and image-guided procedures as they apply to benign and malignant diseases of the genitourinary tract. This flagship journal includes the companion videojournal Videourology™ with every subscription. While Journal of Endourology remains focused on publishing rigorously peer reviewed articles, Videourology accepts original videos containing material that has not been reported elsewhere, except in the form of an abstract or a conference presentation. Journal of Endourology coverage includes: The latest laparoscopic, robotic, endoscopic, and image-guided techniques for treating both benign and malignant conditions Pioneering research articles Controversial cases in endourology Techniques in endourology with accompanying videos Reviews and epochs in endourology Endourology survey section of endourology relevant manuscripts published in other journals.
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