一个国家内不同种族人群与潜在可改变的痴呆危险因素相关的风险差异一项回顾性队列研究使用常规收集的健康数据在新西兰奥特阿瓦。

IF 3.6 3区医学 Q2 GERIATRICS & GERONTOLOGY

International Journal of Geriatric Psychiatry Pub Date : 2025-01-08 DOI:10.1002/gps.70042

Etuini Ma'u, Sarah Cullum, Gary Cheung, Jade Tamatea, Gill Livingston, Naaheed Mukadam

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引用次数: 0

摘要

导言：虽然新西兰（NZ）不同种族的痴呆症个体危险因素的危险因素患病率不同，但尚不清楚这些风险的影响在每个群体中是否相同。方法：本回顾性队列研究确定痴呆事件病例。在对年龄和性别进行调整后，Cox回归模型计算了每个风险因素的痴呆风险比。结果：受教育程度、吸烟、糖尿病、抑郁、体育活动和社会孤立与痴呆症风险增加1.13-1.55倍相关。我们没有证明痴呆风险与高血压、酒精或空气污染之间存在关联。种族间的差异被认为是存在的，但由于研究力度的原因，尚未得到证实。讨论：新西兰不同种族之间痴呆预防潜力的差异可能是由不同的患病率和风险因素影响造成的。公共卫生战略必须针对风险最大的族裔群体量身定制。

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Variation of the Risk Associated With Potentially Modifiable Risk Factors for Dementia Between Ethnic Groups Within One Country. A Retrospective Cohort Study Using Routinely Collected Health Data in Aotearoa New Zealand

Introduction

While risk factor prevalence of individual risk factors for dementia varies between ethnic groups in New Zealand (NZ), it is not known whether the effect of these risks is the same in each group.

Methods

This retrospective cohort study identified incident cases of dementia. Cox regression models calculated the hazard ratio for dementia for each of the risk factors, after adjustment for age and sex.

Results

Education, smoking, diabetes, depression, physical activity and social isolation were associated with a 1.13–1.55 times increased risk of dementia. We did not demonstrate an association between dementia risk and hypertension, alcohol, or air pollution. Differences between ethnic groups is suggested but not confirmed due to study power.

Discussion

Differences in dementia prevention potential between ethnic groups in NZ are potentially contributed to by both differential prevalence and risk factor effects. Public health strategies must be tailored for the ethnic populations at most risk.

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来源期刊

International Journal of Geriatric Psychiatry 医学-精神病学

CiteScore

6.10

自引率

2.50%

发文量

168

审稿时长

4-8 weeks

期刊介绍： The rapidly increasing world population of aged people has led to a growing need to focus attention on the problems of mental disorder in late life. The aim of the Journal is to communicate the results of original research in the causes, treatment and care of all forms of mental disorder which affect the elderly. The Journal is of interest to psychiatrists, psychologists, social scientists, nurses and others engaged in therapeutic professions, together with general neurobiological researchers. The Journal provides an international perspective on the important issue of geriatric psychiatry, and contributions are published from countries throughout the world. Topics covered include epidemiology of mental disorders in old age, clinical aetiological research, post-mortem pathological and neurochemical studies, treatment trials and evaluation of geriatric psychiatry services.