K1/ST1265肺炎克雷伯菌侵袭性感染导致多发性脓肿:病例报告及文献复习

IF 2.9 3区 医学 Q2 INFECTIOUS DISEASES
Infection and Drug Resistance Pub Date : 2025-01-03 eCollection Date: 2025-01-01 DOI:10.2147/IDR.S489161
Lina Chen, Canhu Qiu, Ye Lu, Jianqing Lin, Liping Xu
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引用次数: 0

摘要

近年来,高致病性肺炎克雷伯菌(hvKp)引起了越来越多的关注。糖尿病和血清型K1或K2是侵袭性肝脓肿综合征的危险因素,包括肝脓肿和转移性并发症,如菌血症、脑膜炎、眼内炎和坏死性筋膜炎。同时感染肝、肺、前列腺、脑和眼睛的情况极为罕见。本文报道一名41岁男性患者,有发热伴多饮多尿4天病史,糖尿病未经治疗后病情急剧恶化,并发脓毒症、前列腺脓肿、肺脓肿、肝脓肿、颅内感染及眼内炎。确诊为K1/ST1265高毒力肺炎克雷伯菌感染,经抗生素和脓肿引流治疗,患者仍然死亡。K1/ST1265 hvKp表现出异常高的毒力和侵袭性,需要广泛的认识和警惕的监测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Aggressive Infection by K1/ST1265 Klebsiella pneumoniae Leading to Multiple Abscesses: Case Report and Literature Review.

Hypervirulent Klebsiella pneumoniae (hvKp) has attracted increasing attention in recent years. Diabetes and serotype K1 or K2 are risk factors for invasive liver abscess syndrome including liver abscesses and the metastatic complications such as bacteremia, meningitis, endophthalmitis, and necrotizing fasciitis. Simultaneous infections of the liver, lungs, prostate, brain, and eyes are exceedingly rare. In this paper, a 41-year-old male patient who presented with a 4-day history of fever with polydipsia and polyuria and untreated diabetes deteriorated dramatically with sepsis, prostate abscess, lung abscess, liver abscess and intracranial infection as well as endophthalmitis. He was diagnosed with infection by K1/ST1265 hypervirulent Klebsiella pneumoniae and after treatment with antibiotics and abscess drainage, while the patient still passed away. K1/ST1265 hvKp exhibits exceptionally high virulence and invasiveness, necessitating broad awareness and vigilant monitoring.

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来源期刊
Infection and Drug Resistance
Infection and Drug Resistance Medicine-Pharmacology (medical)
CiteScore
5.60
自引率
7.70%
发文量
826
审稿时长
16 weeks
期刊介绍: About Journal Editors Peer Reviewers Articles Article Publishing Charges Aims and Scope Call For Papers ISSN: 1178-6973 Editor-in-Chief: Professor Suresh Antony An international, peer-reviewed, open access journal that focuses on the optimal treatment of infection (bacterial, fungal and viral) and the development and institution of preventative strategies to minimize the development and spread of resistance.
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