皮肤和肌肉内多发性骨髓瘤的18F-FDG PET/CT成像。

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-02-01 Epub Date: 2024-11-26 DOI:10.1097/RLU.0000000000005579

Brandon Lippold, Amin H Jahromi

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引用次数: 0

摘要

摘要：多发性骨髓瘤的皮肤表现很少见，但与其他髓外表现一样，预后较差。我们提出的情况下，65岁的男性免疫球蛋白G κ多发性骨髓瘤和先前的自体干细胞移植。在随后的治疗中，他出现了多个新的皮肤和皮下左髋关节肿块。这些病变的活检显示浆细胞肿瘤具有间变性形态，证实了疾病的进展。由于难治性疾病，他随后对这些病变进行了放射治疗，并计划进行嵌合抗原受体t细胞治疗。

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18F-FDG PET/CT Imaging of Cutaneous and Intramuscular Multiple Myeloma.

Abstract: Cutaneous manifestations of multiple myeloma are rare but, as with other extramedullary manifestations, carry a worse prognosis. We present the case of a 65-year-old man with immunoglobulin G κ multiple myeloma and prior autologous stem cell transplant. On subsequent therapy, he presented with multiple new cutaneous and subcutaneous left hip masses. Biopsy of these lesions revealed plasma cell neoplasm with anaplastic morphology, confirming progression of disease. He subsequently underwent radiation to these lesions with plans for chimeric antigen receptor T-cell therapy due to refractory disease.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.