Sophie Cormillot, Ryan Dickinson, Marc Weissman, Valerie MacDonald-Dickinson
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Multiple cutaneous mast cell tumors displaying epitheliotropism in a male cat.
A 16-year-old castrated male domestic medium-hair cat was referred for examination of multiple cutaneous mast cell tumors displaying epitheliotropism. Staging tests were negative for distant metastasis. Toceranib phosphate therapy was initiated. The cat improved clinically and had a strong partial response. Tumor progression was noted 13 wk later, at which time the cat was treated with lomustine. The cat was euthanized 11 d later. Epitheliotropism is an uncommon finding in mast cell tumors and may be associated with more aggressive behavior. Key clinical message: Feline cutaneous mast cell tumors displaying epitheliotropism may follow a more aggressive clinical course. Toceranib should be considered as an initial treatment for these tumors. Further research is needed to determine the prognosis for cats with epitheliotropic mast cell tumors.
期刊介绍：
The Canadian Veterinary Journal (CVJ) provides a forum for the discussion of all matters relevant to the veterinary profession. The mission of the Journal is to educate by informing readers of progress in clinical veterinary medicine, clinical veterinary research, and related fields of endeavor. The key objective of The CVJ is to promote the art and science of veterinary medicine and the betterment of animal health.
A report suggesting that animals have been unnecessarily subjected to adverse, stressful, or harsh conditions or treatments will not be processed for publication. Experimental studies using animals will only be considered for publication if the studies have been approved by an institutional animal care committee, or equivalent, and the guidelines of the Canadian Council on Animal Care, or equivalent, have been followed by the author(s).
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