Adrian M Svingos, Rob J Forsyth, Ludvik Alkhoury, Beth S Slomine, Stacy J Suskauer, William D Watson, Laura S Blackwell, Sudhin A Shah
{"title":"建立儿童神经康复中认知和语言量表（CALS）的最小临床重要差异。","authors":"Adrian M Svingos, Rob J Forsyth, Ludvik Alkhoury, Beth S Slomine, Stacy J Suskauer, William D Watson, Laura S Blackwell, Sudhin A Shah","doi":"10.1016/j.apmr.2024.12.020","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>The Cognitive and Linguistic Scale (CALS) was developed to serially monitor cognitive recovery of children and young people after severe acquired brain injury, during inpatient rehabilitation. The CALS can be used to derive Cognitive Ability Estimates (CAE), which are Rasch-propertied (unidimensional, interval-scale) and therefore may be ideally applied for use in research including within the context of clinical trials. Here, we used established statistical distribution-based and expert consensus-based methods to estimate the minimal clinically important difference (MCID) for CAE derived from the CALS.</p><p><strong>Design: </strong>Retrospective study.</p><p><strong>Setting: </strong>Pediatric inpatient rehabilitation hospital.</p><p><strong>Participants: </strong>252 patients consecutively admitted for inpatient rehabilitation after acquired brain injury (46% traumatic brain injury); age at injury ranging from 1.9 to 21.6 years (median, 11.8 years).</p><p><strong>Interventions: </strong>Not applicable.</p><p><strong>Main outcome measures: </strong>MCID estimates.</p><p><strong>Results: </strong>Together, results suggest a MCID of approximately 4-7 CAE units.</p><p><strong>Conclusions: </strong>These data can be used to aid in the design and interpretation of clinical studies proposing to use the CALS CAE as an outcome measure.</p>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.6000,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Establishing Minimal Clinically Important Differences for the Cognitive and Linguistic Scale (CALS) in Pediatric Neurorehabilitation.\",\"authors\":\"Adrian M Svingos, Rob J Forsyth, Ludvik Alkhoury, Beth S Slomine, Stacy J Suskauer, William D Watson, Laura S Blackwell, Sudhin A Shah\",\"doi\":\"10.1016/j.apmr.2024.12.020\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>The Cognitive and Linguistic Scale (CALS) was developed to serially monitor cognitive recovery of children and young people after severe acquired brain injury, during inpatient rehabilitation. The CALS can be used to derive Cognitive Ability Estimates (CAE), which are Rasch-propertied (unidimensional, interval-scale) and therefore may be ideally applied for use in research including within the context of clinical trials. Here, we used established statistical distribution-based and expert consensus-based methods to estimate the minimal clinically important difference (MCID) for CAE derived from the CALS.</p><p><strong>Design: </strong>Retrospective study.</p><p><strong>Setting: </strong>Pediatric inpatient rehabilitation hospital.</p><p><strong>Participants: </strong>252 patients consecutively admitted for inpatient rehabilitation after acquired brain injury (46% traumatic brain injury); age at injury ranging from 1.9 to 21.6 years (median, 11.8 years).</p><p><strong>Interventions: </strong>Not applicable.</p><p><strong>Main outcome measures: </strong>MCID estimates.</p><p><strong>Results: </strong>Together, results suggest a MCID of approximately 4-7 CAE units.</p><p><strong>Conclusions: </strong>These data can be used to aid in the design and interpretation of clinical studies proposing to use the CALS CAE as an outcome measure.</p>\",\"PeriodicalId\":8313,\"journal\":{\"name\":\"Archives of physical medicine and rehabilitation\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.6000,\"publicationDate\":\"2025-01-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of physical medicine and rehabilitation\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.apmr.2024.12.020\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"REHABILITATION\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of physical medicine and rehabilitation","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.apmr.2024.12.020","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"REHABILITATION","Score":null,"Total":0}
Establishing Minimal Clinically Important Differences for the Cognitive and Linguistic Scale (CALS) in Pediatric Neurorehabilitation.
Objective: The Cognitive and Linguistic Scale (CALS) was developed to serially monitor cognitive recovery of children and young people after severe acquired brain injury, during inpatient rehabilitation. The CALS can be used to derive Cognitive Ability Estimates (CAE), which are Rasch-propertied (unidimensional, interval-scale) and therefore may be ideally applied for use in research including within the context of clinical trials. Here, we used established statistical distribution-based and expert consensus-based methods to estimate the minimal clinically important difference (MCID) for CAE derived from the CALS.
Participants: 252 patients consecutively admitted for inpatient rehabilitation after acquired brain injury (46% traumatic brain injury); age at injury ranging from 1.9 to 21.6 years (median, 11.8 years).
Interventions: Not applicable.
Main outcome measures: MCID estimates.
Results: Together, results suggest a MCID of approximately 4-7 CAE units.
Conclusions: These data can be used to aid in the design and interpretation of clinical studies proposing to use the CALS CAE as an outcome measure.
期刊介绍：
The Archives of Physical Medicine and Rehabilitation publishes original, peer-reviewed research and clinical reports on important trends and developments in physical medicine and rehabilitation and related fields. This international journal brings researchers and clinicians authoritative information on the therapeutic utilization of physical, behavioral and pharmaceutical agents in providing comprehensive care for individuals with chronic illness and disabilities.
Archives began publication in 1920, publishes monthly, and is the official journal of the American Congress of Rehabilitation Medicine. Its papers are cited more often than any other rehabilitation journal.
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