低频率和高频率饮食斑马鱼的骨动力学。

IF 1.9 3区生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Comparative Biochemistry and Physiology B-Biochemistry & Molecular Biology Pub Date : 2025-01-03 DOI:10.1016/j.cbpb.2025.111070

Kathryn Bisaha , Simon Bagatto , Rebekah Harden , Randi Depp , Rachel Olson , Qin Liu , Janna M. Andronowski , Richard L. Londraville

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引用次数: 0

摘要

在40 天内分别饲喂高频率和低频率饲料，以评估饲料对斑马鱼骨骼参数的影响。饲喂3次/天（高）的鱼的总重和长度显著大于饲喂2次/周(低；

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Bone dynamics in zebrafish on low- and high-frequency diets

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Bone dynamics in zebrafish on low- and high-frequency diets

Zebrafish (Danio rerio) were fed high and low-frequency diets over 40 days to assess the effect of diet on bone parameters. Fish fed 3×/day (High) were significantly greater in total weight and length vs. fish fed 2×/week (Low; <0.01). The High group had significantly higher vertebral bone density (p = 0.0009) and lower bone volume (p = 0.04) compared to the Low group. Scales from the Low group also had higher density of resorption lacunae in their scales (p = 0.02). We interpret these data to hypothesize that higher leptin titers associated with reduced calorie intake is generally catabolic to bone in zebrafish.

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来源期刊

Comparative Biochemistry and Physiology B-Biochemistry & Molecular Biology 生物-动物学

CiteScore

4.60

自引率

4.50%

发文量

审稿时长

22 days

期刊介绍： Comparative Biochemistry & Physiology (CBP) publishes papers in comparative, environmental and evolutionary physiology. Part B: Biochemical and Molecular Biology (CBPB), focuses on biochemical physiology, primarily bioenergetics/energy metabolism, cell biology, cellular stress responses, enzymology, intermediary metabolism, macromolecular structure and function, gene regulation, evolutionary genetics. Most studies focus on biochemical or molecular analyses that have clear ramifications for physiological processes.