在丹麦的一个大容量中心引入机器人辅助肾移植:试点和可行性研究。

IF 2.2 3区 医学 Q2 SURGERY
Milla Ortved, Julia Dagnæs-Hansen, Hein V Stroomberg, Vladimir Karas, Malene Rohrsted, Søren S Sørensen, Andreas Røder
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引用次数: 0

摘要

与开放式肾移植(OKT)相比,机器人辅助肾移植(RAKT)可能会减少手术并发症,但迄今为止还没有随机试验对此进行探讨。本研究的目的是探索在我们的机构引入RAKT的可行性,使其可用于已故供体移植,并在进行RAKT和OKT的随机对照试验之前评估早期手术结果。RAKT在丹麦哥本哈根大学医院泌尿外科进行。这些患者从2022年6月到2023年5月被纳入研究。这些数据是通过国家电子健康记录收集的。数据包括受体、供体、术中特征、术后90天内并发症(按Clavien-Dindo分级)及存活和出院天数(DAOH)。功能结局包括eGFR、血浆肌酐、移植延迟功能和排斥事件。共进行16次rakt。14例为活体供体移植,2例为已故供体移植。术中无重大不良事件发生,无转归。中位手术时间223 min,中位失血量150 ml,中位住院时间7天,中位DAOH为82。5例患者术后90 d出现7例并发症;然而,没有重大的手术并发症。这项研究在一个小队列中全面评估了RAKT后患者的发病率,结果显示了良好的结果。这支持了我们已经启动的一项比较OKT和RAKT的随机试验(ORAKTx试验)减少并发症的临床假设(NCT标识符05730257)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Introducing robot-assisted kidney transplantation in a high-volume centre in Denmark: a pilot and feasibility study.

Robot-assisted kidney transplantation (RAKT) may reduce surgical complications compared to open kidney transplantation (OKT), but no randomised trials have explored this to date. The aim of the present study is to explore the feasibility of introducing RAKT at our institution, making it available in deceased donor transplantation and evaluate early surgical outcomes prior to performing a randomised trial comparing RAKT to OKT. RAKT was performed at Department of Urology, Copenhagen University Hospital, Rigshospitalet, Denmark. The patients were included from June 2022 until May 2023. The data were collected through the national electronic health records. The data include recipient, donor and intraoperative characteristics, postoperative complications within 90 days graded according to Clavien-Dindo classification and days alive and out of hospital (DAOH). The functional outcomes include eGFR, plasma creatinine, delayed graft function, and rejection episodes. Sixteen RAKTs were performed. Fourteen cases were transplantations with living donors and two cases were with deceased donors. There were no major intra-operative adverse events and no conversions. The median operative time was 223 min and median blood loss 150 ml. The median length of stay was 7 days and median DAOH was 82. Seven complications occurred in five patients at 90 days postoperatively; however, there were no major surgical complications. This study comprehensively assesses patient morbidity following RAKT in a small cohort with results indicating favourable outcomes. This supported our clinical assumption of reduced complications for a randomised trial comparing OKT and RAKT (the ORAKTx trial) which has been initiated (NCT identifier 05730257).

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来源期刊
CiteScore
4.20
自引率
8.70%
发文量
145
期刊介绍: The aim of the Journal of Robotic Surgery is to become the leading worldwide journal for publication of articles related to robotic surgery, encompassing surgical simulation and integrated imaging techniques. The journal provides a centralized, focused resource for physicians wishing to publish their experience or those wishing to avail themselves of the most up-to-date findings.The journal reports on advance in a wide range of surgical specialties including adult and pediatric urology, general surgery, cardiac surgery, gynecology, ENT, orthopedics and neurosurgery.The use of robotics in surgery is broad-based and will undoubtedly expand over the next decade as new technical innovations and techniques increase the applicability of its use. The journal intends to capture this trend as it develops.
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