来自NHANES 2015-2023的一项横断面研究的金属植入物与美国成年人中风的关系

IF 4.1 2区医学 Q2 GERIATRICS & GERONTOLOGY

Frontiers in Aging Neuroscience Pub Date : 2024-12-20 eCollection Date: 2024-01-01 DOI:10.3389/fnagi.2024.1505645

Kai Wu, Liang Pang, Pingping Su, Cunxian Lv

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引用次数: 0

摘要

目的：金属植入物在骨科治疗中起着至关重要的作用，广泛应用于骨折修复、关节置换术和脊柱外科手术。虽然这些植入物通常含有铬（Cr）等关键元素，但其潜在的健康影响，特别是与中风风险的关系，尚未完全阐明。本研究旨在评估金属植入物与中风之间的关系。方法：利用2015年至2023年全国健康与营养调查（NHANES）的数据，我们对12337名美国成年人进行了横断面分析，其中3699名参与者报告有金属种植体，8638名没有。Implant-like。结果：通过logistic回归分析，我们发现金属植入物与卒中风险呈正相关（调整后OR = 1.458,95%CI (1.130, 1.881), p = 0.004）。进一步的分层分析发现，这种正相关在年龄较大和体力活动较少的参与者中更为显著。结论：研究结果表明，金属植入物可能与卒中风险增加有关，但鉴于横断面研究的固有局限性，本研究无法确定因果关系。

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Association between metallic implants and stroke in US adults from NHANES 2015-2023 a cross-sectional study.

Objective: Metal implants play a vital role in orthopedic treatment and are widely used in fracture repair, joint replacement and spinal surgery. Although these implants often contain key elements such as chromium (Cr), their potential health effects, particularly their association with stroke risk, have not been fully elucidated. This study aimed to evaluate the association between metallic implants and stroke.

Methods: Using data from the 2015 to 2023 National Health and Nutrition Examination Survey (NHANES), we conducted a cross-sectional analysis of 12,337 US adults, in which 3,699 participants reported having metal implants and 8,638 without. Implant-like.

Results: Through logistic regression analysis, we revealed a significant positive association between metallic implants and stroke risk (adjusted OR = 1.458, 95%CI (1.130, 1.881), p = 0.004). Further stratified analysis found that this positive association was more significant among older and less physically active participants.

Conclusion: Findings suggest that metallic implants may be associated with an increased risk of stroke, but given the inherent limitations of cross-sectional studies, this study cannot establish causality.

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来源期刊

Frontiers in Aging Neuroscience GERIATRICS & GERONTOLOGY-NEUROSCIENCES

CiteScore

6.30

自引率

8.30%

发文量

1426

期刊介绍： Frontiers in Aging Neuroscience is a leading journal in its field, publishing rigorously peer-reviewed research that advances our understanding of the mechanisms of Central Nervous System aging and age-related neural diseases. Specialty Chief Editor Thomas Wisniewski at the New York University School of Medicine is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.