{"title":"戊酸雌二醇联合中药胶囊治疗卵巢早衰的疗效观察。","authors":"Lu Sun, Xiaodong Fan, Qian Chen, Guoyan Liu","doi":"10.29063/ajrh2024/v28i11.13","DOIUrl":null,"url":null,"abstract":"<p><p>The objective of this study was to examine the efficacy of the concurrent utilization of estradiol valerate and kuntai capsule (a Chinese herbal preparation) in addressing premature ovarian failure (POF) and its ramifications for ovarian hemodynamics and sex hormone levels. A retrospective study of 104 patients with POF was conducted, dividing them into control (n=50) and observation groups (n=54). The control group received estradiol valerate, while the observation group received estradiol valerate and KunTai capsules over 12 weeks. Clinical effectiveness, ovarian pulsatility index (PI), resistance index (RI), hormone levels, ovarian function, and adverse reactions were analyzed. The observation group showed significantly improved PI, RI, LH, FSH, E2 levels, and ovarian function in relative to the control group (P<0.05). We conclude that the concurrent use of estradiol valerate and KunTai capsules improves ovarian hemodynamics and hormone levels, offering significant clinical benefits.</p>","PeriodicalId":7551,"journal":{"name":"African journal of reproductive health","volume":"28 11","pages":"135-140"},"PeriodicalIF":0.7000,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Efficacy of concurrent utilization of estradiol valerate and Chinese herbal capsule in managing premature ovarian failure.\",\"authors\":\"Lu Sun, Xiaodong Fan, Qian Chen, Guoyan Liu\",\"doi\":\"10.29063/ajrh2024/v28i11.13\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The objective of this study was to examine the efficacy of the concurrent utilization of estradiol valerate and kuntai capsule (a Chinese herbal preparation) in addressing premature ovarian failure (POF) and its ramifications for ovarian hemodynamics and sex hormone levels. A retrospective study of 104 patients with POF was conducted, dividing them into control (n=50) and observation groups (n=54). The control group received estradiol valerate, while the observation group received estradiol valerate and KunTai capsules over 12 weeks. Clinical effectiveness, ovarian pulsatility index (PI), resistance index (RI), hormone levels, ovarian function, and adverse reactions were analyzed. The observation group showed significantly improved PI, RI, LH, FSH, E2 levels, and ovarian function in relative to the control group (P<0.05). We conclude that the concurrent use of estradiol valerate and KunTai capsules improves ovarian hemodynamics and hormone levels, offering significant clinical benefits.</p>\",\"PeriodicalId\":7551,\"journal\":{\"name\":\"African journal of reproductive health\",\"volume\":\"28 11\",\"pages\":\"135-140\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2024-11-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"African journal of reproductive health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.29063/ajrh2024/v28i11.13\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"African journal of reproductive health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.29063/ajrh2024/v28i11.13","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
Efficacy of concurrent utilization of estradiol valerate and Chinese herbal capsule in managing premature ovarian failure.
The objective of this study was to examine the efficacy of the concurrent utilization of estradiol valerate and kuntai capsule (a Chinese herbal preparation) in addressing premature ovarian failure (POF) and its ramifications for ovarian hemodynamics and sex hormone levels. A retrospective study of 104 patients with POF was conducted, dividing them into control (n=50) and observation groups (n=54). The control group received estradiol valerate, while the observation group received estradiol valerate and KunTai capsules over 12 weeks. Clinical effectiveness, ovarian pulsatility index (PI), resistance index (RI), hormone levels, ovarian function, and adverse reactions were analyzed. The observation group showed significantly improved PI, RI, LH, FSH, E2 levels, and ovarian function in relative to the control group (P<0.05). We conclude that the concurrent use of estradiol valerate and KunTai capsules improves ovarian hemodynamics and hormone levels, offering significant clinical benefits.
期刊介绍：
The African Journal of Reproductive Health is a multidisciplinary and international journal that publishes original research, comprehensive review articles, short reports, and commentaries on reproductive heath in Africa. The journal strives to provide a forum for African authors, as well as others working in Africa, to share findings on all aspects of reproductive health, and to disseminate innovative, relevant and useful information on reproductive health throughout the continent.
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