[先天性免疫缺陷患者支气管扩张的患病率]。

Karla Korkowski-Uviña, Noemí Gómez-Hernández, Antonio Quintero-Ramos, Felipe de J Contreras-Rodríguez, Margarita Ortega-Cisneros
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引用次数: 0

摘要

目的:了解先天性免疫错误患者支气管扩张的患病率,IgG IV或SC免疫球蛋白剂量和血清IgG水平与总Bhalla评分和支气管扩张严重程度的相关性,血清IgG水平与肺部感染进程的相关性。方法:对18岁以上诊断为IBD的患者进行描述性、观察性、横断面研究。我们回顾了临床记录和计算机轴位断层扫描。结果:纳入38例IBD患者,其中支气管扩张的患病率为36.8%。(肺部感染过程与血清IgG水平的相关性,在2020年和2022年患者中存在差异(p分别= 0.002、0.054、0.030)。支气管扩张严重程度与Bhalla量表总分、IgG IV或SC免疫球蛋白剂量、Spearman’s Rho试验ⅰ血清IgG水平的相关性均为显著相关。结论:IBD患者每3 ~ 4年进行一次胸部断层扫描检查,对及时发现支气管扩张,及时开展治疗,提高患者的生活质量和生存率,降低住院费用具有重要意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Prevalence of bronchiectasis in patients with inborn errors of immunity].

Objective: To establish the prevalence of bronchiectasis, correlate the IgG IV or SC immunoglobulin dose and serum IgG levels with the total Bhalla score and the severity of bronchiectasis and associate serum IgG levels with the development of pulmonary infectious processes in patients with diagnosis of innate errors of immunity.

Methods: A descriptive, observational, cross-sectional study with patients over 18 years of age diagnosed with IBD. Clinical records and computed axial tomography were reviewed.

Results: 38 patients with IBD were included, where the prevalence of bronchiectasis was 36.8%. (Regarding the correlation of pulmonary infectious processes with serum IgG levels, a difference was found in patients from 2020 to 2022 (p= 0.002, 0.054, 0.030 respectively). The correlation of severity of bronchiectasis, total score of Bhalla scale, IgG IV or SC immunoglobulin dose and serum IgG levels by Spearman's Rho test I were found to be significantly correlated.

Conclusion: It is important to perform chest tomography studies every 3-4 years in patients with IBD to detect timely bronchiectasis, initiate treatment in time, improving patients' quality of life and survival rates, and reducing hospital costs.

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