复发性药物洗脱支架、支架内再狭窄（DES-ISR）：流行病学、病理生理及治疗。

IF 5.6 2区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

Progress in cardiovascular diseases Pub Date : 2025-01-01 DOI:10.1016/j.pcad.2024.12.003

Aashish Gupta , Oscar Maitas , Rajan A.G. Patel

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引用次数: 0

摘要

冠状动脉支架内再狭窄（ISR）是由先前放置支架的内膜增生和新动脉粥样硬化驱动的。药物洗脱支架（DES）已被用作ISR初期发作的一线治疗。然而，经常性ISR具有有限的持久救助选择。在这篇文章中，我们回顾了复发性DES- ISR的病理生理、发病率和治疗选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Recurrent drug eluting stent, in-stent restenosis (DES-ISR): Epidemiology, pathophysiology & treatment

Coronary artery in-stent restenosis (ISR) is driven by neointimal hyperplasia and neo‐atherosclerosis in previously placed stents. Drug eluting stents (DES) have been adopted as first line therapy for the initial episode of ISR. However, recurrent ISR has limited durable salvage options. In this article we review the pathophysiology, incidence, and management options of recurrent DES- ISR.

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来源期刊

Progress in cardiovascular diseases 医学-心血管系统

CiteScore

10.90

自引率

6.60%

发文量

审稿时长

7 days

期刊介绍： Progress in Cardiovascular Diseases provides comprehensive coverage of a single topic related to heart and circulatory disorders in each issue. Some issues include special articles, definitive reviews that capture the state of the art in the management of particular clinical problems in cardiology.