荧光成像辅助胸腔镜解剖病变切除术治疗先天性肺畸形。

IF 3.9 2区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES

Scientific Reports Pub Date : 2025-01-04 DOI:10.1038/s41598-025-85404-5

Taozhen He, Xiaoyan Sun, Guowei Che, Dengke Luo, Miao Yuan, Gang Yang, Kaisheng Cheng, Chang Xu

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引用次数: 0

摘要

胸腔镜解剖切除时病灶的划分是治疗儿童先天性肺畸形的基础。现有的病变界限并不总能满足临床实践的需要。本研究旨在探讨近红外荧光成像联合雾化吸入吲哚菁绿在先天性肺畸形患儿胸腔镜解剖病变切除术中的安全性和有效性。在荧光范围内，吲哚菁绿分布到正常肺组织时，产生均匀的绿色荧光区域，病变很少或没有绿色荧光，从而勾画出清晰的荧光病变分界线。在荧光标定的指导下，除1例肺外隔离外，其余患者均成功行胸腔镜解剖病变切除术。

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Fluorescence imaging-assisted thoracoscopic anatomical lesion resection in treating congenital lung malformation.

Identification of lesion demarcation during thoracoscopic anatomical lesion resection is fundamental for treating children with congenital lung malformation. Existing lesion demarcations do not always meet the needs of clinical practice. This study aimed to explore the safety and efficacy of near-infrared fluorescence imaging with nebulized inhalation of indocyanine green for thoracoscopic anatomical lesion resection in children with congenital lung malformation. Under the fluorescence scope, the area of uniform green fluorescence was produced when indocyanine green was distributed into normal lung tissue, and lesions showed little or no green fluorescence, thus delineating a clear fluorescent lesion demarcation. Under the guidance of fluorescent demarcation, all the patients except one case of extralobar sequestration underwent thoracoscopic anatomical lesion resection successfully.

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来源期刊

Scientific Reports Natural Science Disciplines-

CiteScore

7.50

自引率

4.30%

发文量

19567

审稿时长

3.9 months

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