来自单一手性源的两种不同配体的对映异构C-H硼化反应

IF 10.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Science China Chemistry Pub Date : 2024-09-23 DOI:10.1007/s11426-024-2106-3

Rongrong Du, Senmiao Xu

引用次数: 0

摘要

本文报道了一种铱催化的三氟甲基酮衍生腙α- γ -二甲基的对映发散C(sp3)-H硼化反应，构建了一系列具有高水平手性诱导的无环全碳季立体中心。来自同一手性源的两种不同的手性双齿硼基配体不仅可以改变对映选择性，而且在底物范围上是互补的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Enantio-divergent C–H borylation with two different ligands from a single chiral source

Reported here is an iridium-catalyzed enantio-divergent C(sp³)-H borylation of α-gem-dimethyl groups of trifluoromethyl ketone-derived hydrazones to construct a series of acyclic all-carbon quaternary stereocenters with a high level of chiral induction. Two different chiral bidentate boryl ligands from a common chiral source not only can switch the enantioselectivity but also are complementary in terms of the substrate scope.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Science China Chemistry CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

14.40

自引率

7.30%

发文量

3787

审稿时长

2.2 months

期刊介绍： Science China Chemistry, co-sponsored by the Chinese Academy of Sciences and the National Natural Science Foundation of China and published by Science China Press, publishes high-quality original research in both basic and applied chemistry. Indexed by Science Citation Index, it is a premier academic journal in the field. Categories of articles include: Highlights. Brief summaries and scholarly comments on recent research achievements in any field of chemistry. Perspectives. Concise reports on thelatest chemistry trends of interest to scientists worldwide, including discussions of research breakthroughs and interpretations of important science and funding policies. Reviews. In-depth summaries of representative results and achievements of the past 5–10 years in selected topics based on or closely related to the research expertise of the authors, providing a thorough assessment of the significance, current status, and future research directions of the field.