子女被诊断患有精神障碍前后的父母心理病理学:基于人群的匹配队列研究

IF 6.5 1区 医学 Q1 PSYCHIATRY
Hannah Chatwin, Katrine Holde, Theresa Wimberley, Søren Dalsgaard, Liselotte Vogdrup Petersen
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引用次数: 0

摘要

背景:需要更多的研究来了解精神障碍儿童的父母在孩子被诊断之前和之后的精神病理学。在这里,我们估计了有精神障碍的孩子的父母与没有精神障碍的孩子的精神障碍和精神药物使用的风险,以及孩子和父母精神病理之间的时间关联。方法:我们使用丹麦注册数据进行了一项基于人群的匹配队列研究。研究人群包括1999-2014年期间被诊断为感兴趣的精神障碍(注意力缺陷/多动障碍、自闭症谱系障碍、智力障碍、焦虑障碍、情绪障碍、饮食障碍、物质使用障碍和精神分裂症谱系障碍)的所有18岁儿童的父母和匹配的参考人群。每个被诊断出患有精神障碍的孩子与10个相同性别和出生年份的孩子相匹配,这些孩子没有被诊断出患有精神障碍。对于所有父母,我们估计了在孩子诊断前后4年父母精神障碍和精神药物处方的年发生率。结果我们观察到,与参考人群相比,精神障碍儿童的父母患精神障碍和使用精神药物的风险显著增加。平均而言,被诊断患有抑郁症的孩子的父母患情绪障碍、焦虑症以及服用抗抑郁药和抗精神病药的几率是常人的两倍。情绪和焦虑障碍的发生率在儿童诊断前后的1-2年达到高峰。父母处方精神药物(尤其是抗精神病药物)的发生率在儿童被诊断的那一年以及在儿童被诊断为抗抑郁药和睡眠药物之前的3年达到顶峰。结论:本研究表明儿童与父母精神病理之间存在明显的时间关联,父母精神病理在儿童诊断前后的几年达到高峰。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Parental psychopathology before and after the child's diagnosis of a mental disorder: a population‐based matched cohort study
BackgroundMore research is needed to understand psychopathology among parents of children with mental disorders in the years before and after the child is diagnosed. Here, we estimated the risk of mental disorders and psychotropic medication use in parents of children with versus without mental disorders and the temporal associations between child and parental psychopathology.MethodsWe conducted a population‐based matched cohort study using Danish register data. The study population included child–parent pairs of all children diagnosed with a mental disorder of interest (attention‐deficit/hyperactivity disorder, autism spectrum disorder, intellectual disability, anxiety disorder, mood disorder, eating disorder, substance use disorder, and schizophrenia spectrum disorder) by 18 years of age during the period 1999–2014 and a matched reference population. Each child with a diagnosis was matched to 10 children of the same sex and birth year who had not been diagnosed with the mental disorder of interest. For all parents, we estimated the yearly incidence proportion of parental mental disorders and prescriptions for psychotropic medications 4 years before and after the child's diagnosis.ResultsWe observed a substantially increased risk of mental disorders and psychotropic medication use among parents of children with a mental disorder, compared to the reference population. On average, parents of children with a diagnosis had twice the odds of mood disorders, anxiety disorders, and prescriptions for anti‐depressants and anti‐psychotics. The incidence of mood and anxiety disorders peaked in the 1–2 years before and after the child's diagnosis. The incidence of parental prescriptions for psychotropic medications (particularly anti‐psychotics) peaked in the year the child was diagnosed and in the 3 years before the child's diagnosis for anti‐depressants and sleep medications.ConclusionsThis study demonstrates clear temporal associations between child and parental psychopathology, with parental psychopathology peaking in the years immediately before and after the child's diagnosis.
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来源期刊
CiteScore
13.80
自引率
5.30%
发文量
169
审稿时长
1 months
期刊介绍: The Journal of Child Psychology and Psychiatry (JCPP) is a highly regarded international publication that focuses on the fields of child and adolescent psychology and psychiatry. It is recognized for publishing top-tier, clinically relevant research across various disciplines related to these areas. JCPP has a broad global readership and covers a diverse range of topics, including: Epidemiology: Studies on the prevalence and distribution of mental health issues in children and adolescents. Diagnosis: Research on the identification and classification of childhood disorders. Treatments: Psychotherapeutic and psychopharmacological interventions for child and adolescent mental health. Behavior and Cognition: Studies on the behavioral and cognitive aspects of childhood disorders. Neuroscience and Neurobiology: Research on the neural and biological underpinnings of child mental health. Genetics: Genetic factors contributing to the development of childhood disorders. JCPP serves as a platform for integrating empirical research, clinical studies, and high-quality reviews from diverse perspectives, theoretical viewpoints, and disciplines. This interdisciplinary approach is a key feature of the journal, as it fosters a comprehensive understanding of child and adolescent mental health. The Journal of Child Psychology and Psychiatry is published 12 times a year and is affiliated with the Association for Child and Adolescent Mental Health (ACAMH), which supports the journal's mission to advance knowledge and practice in the field of child and adolescent mental health.
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