[Peculiarities of the time of manifestation of a number of diseases in the periods before and after the COVID-19 pandemic according to the data of municipal polyclinics of Sakhalin region.]

The topic of the timing of the manifestation of age-associated diseases (as an indirect indicator of accelerated population aging) after the transfer of COVID-19 remains an urgent area in scientific research. Early targeted diagnosis can significantly reduce the consequences of pathology, in connection with which the features of the manifestation of various nosologies in the post-COVID period were studied. The materials were the accounting and statistical data of the municipal polyclinics of the Sakhalin Region for the pre-COVID (2017-2019) and post-COVID (2022-2023) periods. The median age of newly diagnosed patients and the age-specific incidence index were analyzed for the following nosologies: hypertensive diseases, coronary artery disease, type 2 diabetes mellitus, glaucoma, senile cataracts, and Parkinson's disease. There was a «rejuvenation» of the timing of the manifestation of the disease in the post-COVID period. Meanwhile, the decrease in the median age of disease manifestation was uneven: the most pronounced «rejuvenation» was characteristic of hypertensive diseases, type 2 diabetes mellitus, glaucoma and coronary heart disease. The order of manifestation of the considered nosologies was maintained in both observation periods. This circumstance is confirmed by both the median age of patients and the age-specific incidence index.