关于在氧-臭氧辅助治疗中应用自适应混沌恢复健康状态的臭氧能力。

IF 4.8 2区医学 Q2 IMMUNOLOGY

International immunopharmacology Pub Date : 2025-02-06 DOI:10.1016/j.intimp.2024.113967

Salvatore Chirumbolo , Marianno Franzini , Luigi Valdenassi

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引用次数: 0

摘要

臭氧在医学上的作用是一个有趣的话题，也是一个激烈而有争议的辩论。其作用机制仍远未完全了解。然而，臭氧有可能在生物体中引发一系列与混沌、多稳定现象和振荡过程有关的动力学。臭氧可能参与了适应性混沌。健康中的自适应混沌和病理复杂性的降低是描述生物系统功能动力学的相互关联的现象。适应性混沌是指健康的生物系统所表现出的一种受控、复杂和灵活的行为状态。它允许秩序和不可预测性之间的动态平衡，使系统能够响应各种内部和外部刺激。在病理状态下，系统失去了自适应混沌，经常变得过于僵化或过度混乱。复杂性的降低限制了系统对刺激作出有效反应的能力，使其容易出现功能障碍。本文讨论了臭氧在这些情况下的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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About the ozone ability in using adaptive chaos to restore a healthy state in the oxygen-ozone adjunct therapy

The action of ozone in medicine is a subject of interest and lively, controversial debates. Its mechanisms of action are still far from fully understood. However, it is possible that ozone triggers a series of dynamics in living organisms related to chaos, multi-stable phenomena, and oscillatory processes. Ozone may be involved in adaptive chaos. Adaptive chaos in health and the reduction of complexity in pathology are interconnected phenomena that describe the functional dynamics of biological systems. Adaptive chaos refers to a state of controlled, complex, and flexible behaviour exhibited by healthy biological systems. It allows for a dynamic balance between order and unpredictability, enabling the system to respond to various internal and external stimuli. In pathological states, the system loses its adaptive chaos, often becoming either too rigid or overly chaotic. This reduction in complexity limits the ability of the system to respond effectively to stimuli, making it prone to dysfunction. This paper addresses the role of ozone in these scenarios.

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来源期刊

International immunopharmacology 医学-免疫学

CiteScore

8.40

自引率

3.60%

发文量

935

审稿时长

53 days

期刊介绍： International Immunopharmacology is the primary vehicle for the publication of original research papers pertinent to the overlapping areas of immunology, pharmacology, cytokine biology, immunotherapy, immunopathology and immunotoxicology. Review articles that encompass these subjects are also welcome. The subject material appropriate for submission includes: • Clinical studies employing immunotherapy of any type including the use of: bacterial and chemical agents; thymic hormones, interferon, lymphokines, etc., in transplantation and diseases such as cancer, immunodeficiency, chronic infection and allergic, inflammatory or autoimmune disorders. • Studies on the mechanisms of action of these agents for specific parameters of immune competence as well as the overall clinical state. • Pre-clinical animal studies and in vitro studies on mechanisms of action with immunopotentiators, immunomodulators, immunoadjuvants and other pharmacological agents active on cells participating in immune or allergic responses. • Pharmacological compounds, microbial products and toxicological agents that affect the lymphoid system, and their mechanisms of action. • Agents that activate genes or modify transcription and translation within the immune response. • Substances activated, generated, or released through immunologic or related pathways that are pharmacologically active. • Production, function and regulation of cytokines and their receptors. • Classical pharmacological studies on the effects of chemokines and bioactive factors released during immunological reactions.