伊朗北部拉什特Velayat教学医院住院烧伤患者念珠菌的微生物学、流行病学、危险因素和临床治疗

IF 1.3 Q4 MICROBIOLOGY

Iranian Journal of Microbiology Pub Date : 2024-12-01 DOI:10.18502/ijm.v16i6.17262

Zahra Rafat, Davoud Roostaei, Mohammadreza Mobayen, Hamid Salehiniya, Parimah Pournasrolah

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引用次数: 0

摘要

背景与目的：本研究旨在了解伊朗拉什特Velayat医院住院烧伤患者念珠菌的流行病学及临床治疗。材料与方法：对疑似患者血样进行培养，并进行pcr测序。采用CLSI M27-A4文件进行抗真菌药敏试验。结果：4份血样呈阳性。假丝酵母菌假丝酵母菌复合体（4.75%中的3例）是导致假丝酵母菌感染的主要原因。MIC值显示所有菌株对伊曲康唑、两性霉素B和5-氟胞嘧啶敏感。结论：在抗真菌治疗中应注意非白色念珠菌的种类。

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The microbiology, epidemiology, risk factors, and clinical therapy of candidemia in burn patients hospitalized in Velayat Teaching Hospital, Rasht, northern Iran.

Background and objectives: The study aimed to investigate the epidemiology and clinical therapy of candidemia in burn patients hospitalized in Velayat Hospital, Rasht, Iran.

Materials and methods: The blood samples of suspected patients were cultured and PCR-sequencing was performed. Antifungal susceptibility testing was done by the CLSI M27-A4 document.

Results: Four blood samples were identified as positive. Candida parapsilosis complex (3 out of 4, 75%) was the predominant leading cause of candidemia. MIC values showed that all isolates were susceptible to itraconazole, amphotericin B, and 5-flucytosine.

Conclusion: It seems necessary to pay attention to Candida non-albicans species in antifungal therapy.

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来源期刊

Iranian Journal of Microbiology MICROBIOLOGY-

CiteScore

2.40

自引率

7.10%

发文量

审稿时长

12 weeks

期刊介绍： The Iranian Journal of Microbiology (IJM) is an international, multi-disciplinary, peer-reviewed journal that provides rapid publication of the most advanced scientific research in the areas of basic and applied research on bacteria and other micro-organisms, including bacteria, viruses, yeasts, fungi, microalgae, and protozoa concerning the development of tools for diagnosis and disease control, epidemiology, antimicrobial agents, clinical microbiology, immunology, Genetics, Genomics and Molecular Biology. Contributions may be in the form of original research papers, review articles, short communications, case reports, technical reports, and letters to the Editor. Research findings must be novel and the original data must be available for review by the Editors, if necessary. Studies that are preliminary, of weak originality or merely descriptive as well as negative results are not appropriate for the journal. Papers considered for publication must be unpublished work (except in an abstract form) that is not under consideration for publication anywhere else, and all co-authors should have agreed to the submission. Manuscripts should be written in English.