高分子材料制备微针的方法

IF 2.9 4区工程技术 Q2 CHEMISTRY, MULTIDISCIPLINARY

Korean Journal of Chemical Engineering Pub Date : 2024-10-24 DOI:10.1007/s11814-024-00314-y

Hyewon Choi, Hyein Seo, Hyunsik Yoon

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引用次数: 0

摘要

在生物医学行业中，微针作为一种无痛的皮肤和透皮给药方法获得了极大的关注。根据其预期用途，微针可以制成各种尺寸、形状和材料。为了提高皮肤渗透性，使用一系列微加工技术开发了多功能微针。本文综述了高分子材料微针的制备方法，高分子材料因其易于加工而受到微尺度制造的青睐。此外，我们还讨论了通过在聚合物微针表面涂上金属薄膜或无机纳米颗粒来提高其坚固性的方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Fabrication Methods of Microneedles with Polymeric Materials

In the biomedical industry, microneedles have gained significant attention as a painless method for dermal and transdermal drug delivery. Depending on their intended use, microneedles can be fabricated in various sizes, shapes, and materials. To enhance skin permeability, versatile microneedles have been developed using a range of microfabrication technologies. This review focuses on the fabrication methods of microneedles made from polymeric materials, which are favored for microscale fabrication due to their ease of processing. Additionally, we discuss methods to improve the robustness of polymeric microneedles by coating them with metallic films or inorganic nanoparticles.

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来源期刊

Korean Journal of Chemical Engineering 工程技术-工程：化工

CiteScore

4.60

自引率

11.10%

发文量

310

审稿时长

4.7 months

期刊介绍： The Korean Journal of Chemical Engineering provides a global forum for the dissemination of research in chemical engineering. The Journal publishes significant research results obtained in the Asia-Pacific region, and simultaneously introduces recent technical progress made in other areas of the world to this region. Submitted research papers must be of potential industrial significance and specifically concerned with chemical engineering. The editors will give preference to papers having a clearly stated practical scope and applicability in the areas of chemical engineering, and to those where new theoretical concepts are supported by new experimental details. The Journal also regularly publishes featured reviews on emerging and industrially important subjects of chemical engineering as well as selected papers presented at international conferences on the subjects.