双侧可逆性角膜水肿是左乙拉西坦的新副作用- 1例报告。

IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL
International Medical Case Reports Journal Pub Date : 2024-12-23 eCollection Date: 2024-01-01 DOI:10.2147/IMCRJ.S497262
Kimberly Caruana, Matthew Ellul, Andre Grixti
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引用次数: 0

摘要

目的:我们报告一例左乙拉西坦引起的角膜水肿。据我们所知,这是第一个记录的双侧可逆性角膜水肿继发于左乙拉西坦的病例。患者和方法:一名59岁女性因数周的双侧视力模糊病史被转介至眼科。她是一个已知的继发性进行性多发性硬化症病例,鉴于新的癫痫发作活动,她在转诊前几周由她的神经科医生开始使用左乙拉西坦。检查发现双侧明显的角膜水肿,角膜地形图显示。结果:左乙拉西坦剂量减少后,症状开始改善,最终完全停药。随访患者视力及角膜水肿恢复正常。结论:当患者使用左乙拉西坦出现角膜水肿时,应牢记这一新的副作用,因为这可以避免误诊和不必要的干预。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bilateral Reversible Corneal Edema as a Novel Side-Effect of Levetiracetam - A Case Report.

Purpose: We present a case of levetiracetam-induced corneal edema. To the best of our knowledge, this is the first documented case of bilateral reversible corneal edema secondary to levetiracetam use.

Patients and methods: A 59-year-old woman was referred to the ophthalmology department with a few weeks' history of bilateral blurring of vision. She is a known case of secondary progressive multiple sclerosis, and she was started on levetiracetam by her neurologist a few weeks prior to referral in view of new seizure activity. Examination revealed bilateral clinically evident corneal edema, which was documented on corneal topography.

Results: Upon levetiracetam dose reduction, symptoms started to improve and eventually the medication was stopped altogether. The patient's vision and corneal edema normalized on follow-up.

Conclusion: This novel side effect should be kept in mind when a patient who is on levetiracetam presents with corneal edema as this can avoid misdiagnosis and unnecessary interventions.

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来源期刊
International Medical Case Reports Journal
International Medical Case Reports Journal MEDICINE, GENERAL & INTERNAL-
CiteScore
1.40
自引率
0.00%
发文量
135
审稿时长
16 weeks
期刊介绍: International Medical Case Reports Journal is an international, peer-reviewed, open access, online journal publishing original case reports from all medical specialties. Submissions should not normally exceed 3,000 words or 4 published pages including figures, diagrams and references. As of 1st April 2019, the International Medical Case Reports Journal will no longer consider meta-analyses for publication.
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