双重打击：一例免疫检查点抑制剂结肠炎和合并巨细胞病毒结肠炎患者在纳武单抗。

IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY

ACG Case Reports Journal Pub Date : 2024-12-27 eCollection Date: 2025-01-01 DOI:10.14309/crj.0000000000001569

Misha Gautam, Vinay Jahagirdar, Himil Mahadevia, Kimberly Sanders, John P Campbell, Pamela B Sylvestre, Rajiv Chhabra, Wendell Clarkston, Sreenivasa S Jonnalagadda

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引用次数: 0

摘要

免疫检查点抑制剂通常会引起胃肠道免疫相关的不良反应。这些患者也有更高的并发感染风险。66岁男性免疫检查点抑制剂结肠炎被发现并发耶尔森氏菌和巨细胞病毒结肠炎。这种感染可模拟或使病程复杂化。因此，临床医生必须监测患者的症状，降低感染检测和结肠镜检查的阈值，并考虑治疗策略以减轻其风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Double Whammy: A Case Report of Immune Checkpoint Inhibitor Colitis and Concomitant Cytomegalovirus Colitis in a Patient on Nivolumab.

Immune checkpoint inhibitors commonly cause gastrointestinal immune-related adverse effects. These patients also carry an increased risk of concomitant infections. This 66-year-old man with immune checkpoint inhibitor colitis was discovered to have concurrent Yersinia and Cytomegalovirus colitis. Such infections may mimic or complicate disease course. Hence, clinicians must monitor patient symptoms, have a low threshold for infectious testing and colonoscopy, and consider treatment strategies to mitigate their risk.

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来源期刊

ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-

自引率

14.30%

发文量

170

审稿时长

12 weeks

期刊介绍： ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.