【抗癫痫药物所致耳毒性】。

Q3 Medicine

Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova Pub Date : 2024-01-01 DOI:10.17116/jnevro202412412114

S G Burd, A V Lebedeva, Yu V Rubleva, A P Efimenko, N V Pantina, A V Yurchenko, M A Bogomazova, I I Kovaleva, G A Alekseeva

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引用次数: 0

摘要

根据文献，一些抗癫痫药物（AEDs）有耳毒性作用。使用aed导致听力障碍的机制尚不清楚。药物耳蜗毒性作用的主要临床表现为：耳鸣、感音神经性听力丧失、音高感知受损、听觉亢进。这些疾病可以是可逆的，也可以是不可逆的。主治医师在给以前有听力障碍的患者开抗癫痫药时应谨慎，并及时诊断听力损失，随后进行抗癫痫治疗纠正。

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[Ototoxicity caused by anti-epileptic drugs].

According to the literature, a number of anti-epileptic drugs (AEDs) have an ototoxic effect. The mechanism of hearing dysfunction due to the use of AEDs is not well known. The main clinical manifestations of the cochleotoxic effect of the drugs are: tinnitus, sensorineural hearing loss, impaired pitch perception, hyperacusis. These disorders can be reversible and irreversible. Attending physicians should be careful when prescribing AEDs to patients who have had hearing impairment before, as well as diagnose hearing loss in a timely manner with subsequent correction of anti-epileptic therapy.

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来源期刊

Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova 医学-精神病学

CiteScore

1.10

自引率

0.00%

发文量

287

审稿时长

3-6 weeks

期刊介绍： Одно из старейших медицинских изданий России, основанное в 1901 году. Создание журнала связано с именами выдающихся деятелей отечественной медицины, вошедших в историю мировой психиатрии и неврологии, – С.С. Корсакова и А.Я. Кожевникова. Широкий диапазон предлагаемых журналом материалов и разнообразие форм их представления привлекают внимание научных работников и врачей, опытных и начинающих медиков, причем не только неврологов и психиатров, но и специалистов смежных областей медицины.