大麻二酚补充剂在罗马尼亚:弥合市场声称和临床现实之间的差距。

IF 2 Q3 PHARMACOLOGY & PHARMACY
Pharmacy Pub Date : 2024-11-25 DOI:10.3390/pharmacy12060176
Corina Andrei, George Mihai Nitulescu, Georgiana Nitulescu, Anca Zanfirescu
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引用次数: 0

摘要

近年来,包括罗马尼亚在内的欧洲市场大力推广以大麻二酚(CBD)为基础的产品,这些产品通常被标榜为各种健康状况的有效治疗方法。这项研究调查了与这些补充剂相关的健康声明与临床试验证据之间的不一致性。为了确定罗马尼亚市场上可用的产品,对专门销售cbd产品的在线药店和网站进行了系统审查。此外,对临床试验进行了系统回顾,以评估CBD对特定适应症的疗效。我们的分析显示,一些索赔,如与创伤后应激障碍有关的索赔,缺乏实质性的临床证据。此外,即使有临床支持,补充剂的推荐剂量也往往明显低于试验中使用的剂量,这引起了人们对其功效的担忧。这些发现强调需要更严格的监管和更透明的沟通,以确保消费者的期望与科学证据相一致,最终促进知情决策和消费者安全。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cannabidiol Supplements in Romania: Bridging the Gap Between Marketed Claims and Clinical Reality.

In recent years, the European market, including Romania, has witnessed a significant increase in the promotion of cannabidiol (CBD)-based products, often presented as effective treatments for various health conditions. This study investigates the inconsistencies between the health claims associated with these supplements and the evidence from clinical trials. To identify products available on the Romanian market, a systematic review of online pharmacies and websites that specialize in selling CBD-based products has been performed. Additionally, a systematic review of clinical trials has been conducted to assess the efficacy of CBD for the specified indications. Our analysis revealed that some claims, such as those related to post-traumatic stress disorder, lack substantial clinical evidence. Moreover, even when clinical support exists, the dosages recommended for the supplements are often significantly lower than those used in trials, raising concerns about their efficacy. These findings highlight the need for stricter regulatory oversight and more transparent communication to ensure that consumer expectations are aligned with scientific evidence, ultimately promoting informed decision-making and consumer safety.

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来源期刊
Pharmacy
Pharmacy PHARMACOLOGY & PHARMACY-
自引率
9.10%
发文量
141
审稿时长
11 weeks
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