D A Bazyka, K V Kuts, I V Perchuk, G Y Kreinis, K Y Antipchuk, Z L Vasylenko, M S Hryhorenko
{"title":"清理切尔诺贝利事故后果参与者和从冠状病毒病(covid-19)中康复的乌克兰国防军军事人员的电生理变化。","authors":"D A Bazyka, K V Kuts, I V Perchuk, G Y Kreinis, K Y Antipchuk, Z L Vasylenko, M S Hryhorenko","doi":"10.33145/2304-8336-2024-29-271-294","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>to conduct a clinical and neurophysiological study of Chornobyl clean-up workers and military personnelof the Armed Forces of Ukraine (AFU) with previous coronavirus disease (COVID-19) and individuals of the comparison groups to study the impact of long-term effects of ionizing radiation, psychoemotional stress and previouscoronavirus infection on cerebral functioning.</p><p><strong>Materials and methods: </strong>A prospective clinical study of Chornobyl clean-up workers and servicemen of the ArmedForces of Ukraine (AFU) who had coronavirus disease (COVID-19) and individuals of the comparison groups. Themain group - 30 males participated in liquidating the consequences of the Chornobyl Nuclear Power Plant (ChNPP)accident with previously verified COVID-19 (Chornobyl clean-up workers). As a nosological control group (NCG), 24men with verified chronic cerebrovascular disorder (CVD) not exposed to radiation sources, war-associated psychoemotional stress, and COVID-19 were examined in 2020-2022. Depending on the history of COVID-19, the AFU servicemen were divided into 2 subgroups: «COVID+» and «COVID-». The diagnosis of neuropsychiatric disorders wasestablished according to ICD-10. Visual and spectral EEG analyses assessed cerebral functions in passive wakefulness (rsEEG).</p><p><strong>Results: </strong>Chornobyl clean-up workers «COVID+» and NCG groups did not differ significantly in clinical neuropsychiatric features, except for a higher frequency of organic personality disorder (F07) in the group of the Chornobyl cleanworkers «COVID+» (p < 0.001). In the group of the Chornobyl clean workers «COVID+» relative ( %) spectral deltapower of EEG was significantly diffusely increased as well as absolute spectral delta-power in the left posterior-temporal area compared to NCG (p < 0.05). A significant diffuse increase in relative spectral theta-power with a bilateral excess in parietal areas (p < 0.05 - 0.01), as well as a significant increase in absolute spectral theta-power bilaterally in frontal areas (p < 0.05) was found in the group AFU «COVID+», compared to the group AFU «COVID-».</p><p><strong>Conclusions: </strong>For the first time, a pronounced diffuse slowing of cerebral bioelectrical activity to delta-frequencieswas detected in the Chornobyl clean-up workers being COVID-19 recuperates compared to the comparison groupwith chronic CVD. The AFU servicemen with previous COVID-19 have moderate persistent cerebral dysfunction. Thesechanges require further observation and study.</p>","PeriodicalId":20491,"journal":{"name":"Problemy radiatsiinoi medytsyny ta radiobiolohii","volume":" 29","pages":"271-294"},"PeriodicalIF":0.0000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"ELECTROPHYSIOLOGICAL CHANGES IN THE PARTICIPANTS OF THE LIQUIDATION OF THE CONSEQUENCES OF THE CHORNOBYL ACCIDENT AND THE MILITARY PERSONNEL OF THE UKRAINIAN DEFENSE FORCES RECOVERING FROM CORONAVIRUS DISEASE (COVID-19).\",\"authors\":\"D A Bazyka, K V Kuts, I V Perchuk, G Y Kreinis, K Y Antipchuk, Z L Vasylenko, M S Hryhorenko\",\"doi\":\"10.33145/2304-8336-2024-29-271-294\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>to conduct a clinical and neurophysiological study of Chornobyl clean-up workers and military personnelof the Armed Forces of Ukraine (AFU) with previous coronavirus disease (COVID-19) and individuals of the comparison groups to study the impact of long-term effects of ionizing radiation, psychoemotional stress and previouscoronavirus infection on cerebral functioning.</p><p><strong>Materials and methods: </strong>A prospective clinical study of Chornobyl clean-up workers and servicemen of the ArmedForces of Ukraine (AFU) who had coronavirus disease (COVID-19) and individuals of the comparison groups. Themain group - 30 males participated in liquidating the consequences of the Chornobyl Nuclear Power Plant (ChNPP)accident with previously verified COVID-19 (Chornobyl clean-up workers). As a nosological control group (NCG), 24men with verified chronic cerebrovascular disorder (CVD) not exposed to radiation sources, war-associated psychoemotional stress, and COVID-19 were examined in 2020-2022. Depending on the history of COVID-19, the AFU servicemen were divided into 2 subgroups: «COVID+» and «COVID-». The diagnosis of neuropsychiatric disorders wasestablished according to ICD-10. Visual and spectral EEG analyses assessed cerebral functions in passive wakefulness (rsEEG).</p><p><strong>Results: </strong>Chornobyl clean-up workers «COVID+» and NCG groups did not differ significantly in clinical neuropsychiatric features, except for a higher frequency of organic personality disorder (F07) in the group of the Chornobyl cleanworkers «COVID+» (p < 0.001). In the group of the Chornobyl clean workers «COVID+» relative ( %) spectral deltapower of EEG was significantly diffusely increased as well as absolute spectral delta-power in the left posterior-temporal area compared to NCG (p < 0.05). A significant diffuse increase in relative spectral theta-power with a bilateral excess in parietal areas (p < 0.05 - 0.01), as well as a significant increase in absolute spectral theta-power bilaterally in frontal areas (p < 0.05) was found in the group AFU «COVID+», compared to the group AFU «COVID-».</p><p><strong>Conclusions: </strong>For the first time, a pronounced diffuse slowing of cerebral bioelectrical activity to delta-frequencieswas detected in the Chornobyl clean-up workers being COVID-19 recuperates compared to the comparison groupwith chronic CVD. The AFU servicemen with previous COVID-19 have moderate persistent cerebral dysfunction. Thesechanges require further observation and study.</p>\",\"PeriodicalId\":20491,\"journal\":{\"name\":\"Problemy radiatsiinoi medytsyny ta radiobiolohii\",\"volume\":\" 29\",\"pages\":\"271-294\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Problemy radiatsiinoi medytsyny ta radiobiolohii\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33145/2304-8336-2024-29-271-294\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Problemy radiatsiinoi medytsyny ta radiobiolohii","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33145/2304-8336-2024-29-271-294","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
ELECTROPHYSIOLOGICAL CHANGES IN THE PARTICIPANTS OF THE LIQUIDATION OF THE CONSEQUENCES OF THE CHORNOBYL ACCIDENT AND THE MILITARY PERSONNEL OF THE UKRAINIAN DEFENSE FORCES RECOVERING FROM CORONAVIRUS DISEASE (COVID-19).
Objective: to conduct a clinical and neurophysiological study of Chornobyl clean-up workers and military personnelof the Armed Forces of Ukraine (AFU) with previous coronavirus disease (COVID-19) and individuals of the comparison groups to study the impact of long-term effects of ionizing radiation, psychoemotional stress and previouscoronavirus infection on cerebral functioning.
Materials and methods: A prospective clinical study of Chornobyl clean-up workers and servicemen of the ArmedForces of Ukraine (AFU) who had coronavirus disease (COVID-19) and individuals of the comparison groups. Themain group - 30 males participated in liquidating the consequences of the Chornobyl Nuclear Power Plant (ChNPP)accident with previously verified COVID-19 (Chornobyl clean-up workers). As a nosological control group (NCG), 24men with verified chronic cerebrovascular disorder (CVD) not exposed to radiation sources, war-associated psychoemotional stress, and COVID-19 were examined in 2020-2022. Depending on the history of COVID-19, the AFU servicemen were divided into 2 subgroups: «COVID+» and «COVID-». The diagnosis of neuropsychiatric disorders wasestablished according to ICD-10. Visual and spectral EEG analyses assessed cerebral functions in passive wakefulness (rsEEG).
Results: Chornobyl clean-up workers «COVID+» and NCG groups did not differ significantly in clinical neuropsychiatric features, except for a higher frequency of organic personality disorder (F07) in the group of the Chornobyl cleanworkers «COVID+» (p < 0.001). In the group of the Chornobyl clean workers «COVID+» relative ( %) spectral deltapower of EEG was significantly diffusely increased as well as absolute spectral delta-power in the left posterior-temporal area compared to NCG (p < 0.05). A significant diffuse increase in relative spectral theta-power with a bilateral excess in parietal areas (p < 0.05 - 0.01), as well as a significant increase in absolute spectral theta-power bilaterally in frontal areas (p < 0.05) was found in the group AFU «COVID+», compared to the group AFU «COVID-».
Conclusions: For the first time, a pronounced diffuse slowing of cerebral bioelectrical activity to delta-frequencieswas detected in the Chornobyl clean-up workers being COVID-19 recuperates compared to the comparison groupwith chronic CVD. The AFU servicemen with previous COVID-19 have moderate persistent cerebral dysfunction. Thesechanges require further observation and study.