免提颈动脉多普勒可以识别自发循环而不中断心肺复苏:一项动物研究。

IF 2.8 Q2 CRITICAL CARE MEDICINE
Bjørn Ove Faldaas, Benjamin Stage Storm, Knut Tore Lappegård, Ole-Jakob How, Bent Aksel Nilsen, Gabriel Kiss, Eirik Skogvoll, Erik Waage Nielsen, Hans Torp, Charlotte Björk Ingul
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引用次数: 0

摘要

背景:在心肺复苏(CPR)过程中识别自发循环是具有挑战性的。目前的方法包括间歇性和耗时的脉搏检查,需要暂停胸外按压。这个问题在医院内和院外的心脏骤停情况下都是有问题的,在这些情况下,在心肺复苏术中识别循环的资源可能有限。胸部按压的比例在提高生存率方面起着关键作用。为了应对这一挑战,我们评估了一种新开发的免提、连续颈动脉多普勒系统(RescueDoppler),该系统旨在识别胸外按压过程中的自发循环。在我们的研究中,我们利用猪心脏骤停模型来研究心室颤动的序列,随后进行除颤,并用颈动脉多普勒系统监测胸按压过程中自发循环的恢复。我们研究了每分钟100次和50次的手动按压和机械按压。为了估计检出率(即灵敏度),我们采用了一个logistic混合模型,其中动物身份作为随机效应。结果:离线分析多普勒彩色m模式和光谱显示成功地识别了所有压缩模型的胸按压过程中的自发循环。59个序列中有51个检测到自发循环,预期灵敏度为98%,95%置信区间为59%至99%。结论:RescueDoppler是一种连续的免手颈动脉多普勒系统,在手动和机械胸外按压过程中识别自发循环的预期灵敏度为98%。需要进一步的临床研究来验证这些发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A hands-free carotid Doppler can identify spontaneous circulation without interrupting cardiopulmonary resuscitation: an animal study.

Background: Identifying spontaneous circulation during cardiopulmonary resuscitation (CPR) is challenging. Current methods, which involve intermittent and time-consuming pulse checks, necessitate pauses in chest compressions. This issue is problematic in both in-hospital cardiac arrest and out-of-hospital cardiac arrest situations, where resources for identifying circulation during CPR may be limited. The fraction of chest compression plays a pivotal role in improving survival rates. To address this challenge, we evaluated a newly developed hands-free, continuous carotid Doppler system (RescueDoppler), designed to identify spontaneous circulation during chest compressions. In our study, we utilized a porcine model of cardiac arrest to investigate sequences of ventricular fibrillation, followed by defibrillation, and monitoring for the return of spontaneous circulation during chest compressions with the carotid Doppler system. We explored both manual compressions at 100 and 50 compressions per minute and mechanical compressions. To estimate the detection rate (i.e., sensitivity), we employed a logistic mixed model with animal identity as random effect.

Results: Offline analysis of Doppler color M-mode and spectral display successfully identified spontaneous circulation during chest compressions in all compression models. Spontaneous circulation was detected in 51 of 59 sequences, yielding an expected sensitivity of 98% with a 95% confidence interval of 59% to 99%.

Conclusion: The RescueDoppler, a continuous hands-free carotid Doppler system, demonstrates an expected sensitivity of 98% for identifying spontaneous circulation during both manual and mechanical chest compressions. Clinical studies are needed to further validate these findings.

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来源期刊
Intensive Care Medicine Experimental
Intensive Care Medicine Experimental CRITICAL CARE MEDICINE-
CiteScore
5.10
自引率
2.90%
发文量
48
审稿时长
13 weeks
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