未接种疫苗的旅客感染致命登革热病毒。

IF 3.7 3区医学 Q2 INFECTIOUS DISEASES

European Journal of Clinical Microbiology & Infectious Diseases Pub Date : 2024-12-28 DOI:10.1007/s10096-024-05021-4

Jonathan Steinke, Veronica Di Cristanziano, Jan-Hendrik Naendrup, Dániel Cadar, Martin Gabriel, Roger Grosser, Noëlle Sieg, Lisa Altenrath, Jesko Welters, Alexander Simonis, Rosanne Sprute, Jorge Garcia Borrega, Gertrud Steger, Jonas Schmidt-Chanasit, Alexander Shimabukuro-Vornhagen, Henning Gruell

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引用次数: 0

摘要

登革热对居住或访问流行国家的个人构成越来越大的威胁。已经有了有效的疫苗，但通常只建议在旅行者中使用有记录的先前感染的个人。我们报告了一例严重登革热的致命病例，这名未接种疫苗的旅行者没有已知的登革热病毒感染，但有继发感染的纵向血清学和分子证据。在本病例和旅行者疫苗接种指南的背景下，我们讨论了疫苗接种前筛查、对前往持续暴发地区的旅行者的潜在影响，并强调了血清状态无关疫苗的重要性。

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Fatal dengue virus infection in an unvaccinated traveler.

Dengue is an increasing threat to individuals living in or visiting endemic countries. Effective vaccines have become available, but their use in travelers is typically only recommended to individuals with documented prior infection. We present a fatal case of severe dengue in an unvaccinated traveler without known prior dengue virus infection but longitudinal serologic and molecular evidence for secondary infection. In the context of this case and vaccination guidance for travelers, we discuss pre-vaccination screening, potential implications for travelers to regions with ongoing outbreaks, and emphasize the importance of serostatus-independent vaccines.

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来源期刊

European Journal of Clinical Microbiology & Infectious Diseases 医学-传染病学

CiteScore

10.40

自引率

2.20%

发文量

138

审稿时长

1 months

期刊介绍： EJCMID is an interdisciplinary journal devoted to the publication of communications on infectious diseases of bacterial, viral and parasitic origin.