噪声性听力损失诊断指南及其特异性。

IF 1.7 4区 医学 Q2 OTORHINOLARYNGOLOGY
Mark E Lutman, John de Carpentier, Kevin Green
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引用次数: 0

摘要

目的:Moore, Lowe和Cox最近的一篇论文提出了诊断噪声性听力损失(NIHL)的指南。它在这里被称为MLC指南。我们的目的是评估这些指南的特异性(即不存在假阳性结果),并与已有的指南进行比较。设计:我们将MLC指南和已有指南应用于三个数据集,这些数据集由没有物质噪声暴露史的成年人组成,因此不可能患有NIHL。环境:国家卫生服务(NHS)耳鼻喉科诊所。参与者:536名听力困难和/或耳鸣的患者,否认物质噪音暴露。还评估了两项关于听力的大型档案人口研究,其中包括3250名没有物质噪音暴露的参与者。主要结果测量:指南假阳性结果。结果:MLC指南总体上显示了中等或高的假阳性率,其大小取决于噪声暴露场景以及是否考虑临床或人群样本。对于适用于稳定宽带噪声暴露的程序,总体样本中的假阳性率平均为56%,而以前的指南为31%。对于暴露于强烈的脉冲声音,MLC指南采取了不同的方法,假阳性率在人群样本中约为70%,在临床样本中甚至更高。对于暴露于强烈的色调,MLC指南采取了另一种方法,假阳性率达到80%。结论:MLC指南的特异性比以前的指南差。医学专家应该意识到它们的低特异性和相应的NIHL假阳性诊断的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Guidelines for Diagnosis of Noise-Induced Hearing Loss and Their Specificity.

Objectives: A recent paper by Moore, Lowe and Cox has proposed guidelines for diagnosing noise-induced hearing loss (NIHL). It is referred to here as the MLC guidelines. Our aim was to assess the specificity of those guidelines (i.e., freedom from false-positive outcomes) and compare with pre-existing guidelines.

Design: We applied the MLC guidelines and pre-existing guidelines to three data sets composed of adults who do not have a history of material noise exposure and therefore cannot have NIHL.

Setting: National Health Service (NHS) ENT clinic.

Participants: Five hundred thirty-six patients with hearing difficulty and/or tinnitus who denied material noise exposure. Two large archival population studies of hearing were also assessed, which included 3250 participants without material noise exposure.

Main outcome measure: False-positive outcome from guidelines.

Results: The MLC guidelines demonstrated moderate or high false-positive rates overall, the magnitude depending on the noise exposure scenario and whether clinical or population samples were considered. For the procedure applicable to steady broadband noise exposure, the false-positive rate averaged 56% in the population samples, compared to 31% for previous guidelines. For exposure to intense impulse sounds, the MLC guidelines take a different approach and the false-positive rate was about 70% in the population samples and even higher in the clinic sample. For exposure to intense tones, the MLC guidelines take yet another approach and the false-positive rate reached 80%.

Conclusions: The MLC guidelines demonstrate poorer specificity than previous guidelines. Medical experts should be aware of their poor specificity and consequential likelihood of false-positive diagnoses of NIHL.

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来源期刊
Clinical Otolaryngology
Clinical Otolaryngology 医学-耳鼻喉科学
CiteScore
4.00
自引率
4.80%
发文量
106
审稿时长
>12 weeks
期刊介绍: Clinical Otolaryngology is a bimonthly journal devoted to clinically-oriented research papers of the highest scientific standards dealing with: current otorhinolaryngological practice audiology, otology, balance, rhinology, larynx, voice and paediatric ORL head and neck oncology head and neck plastic and reconstructive surgery continuing medical education and ORL training The emphasis is on high quality new work in the clinical field and on fresh, original research. Each issue begins with an editorial expressing the personal opinions of an individual with a particular knowledge of a chosen subject. The main body of each issue is then devoted to original papers carrying important results for those working in the field. In addition, topical review articles are published discussing a particular subject in depth, including not only the opinions of the author but also any controversies surrounding the subject. • Negative/null results In order for research to advance, negative results, which often make a valuable contribution to the field, should be published. However, articles containing negative or null results are frequently not considered for publication or rejected by journals. We welcome papers of this kind, where appropriate and valid power calculations are included that give confidence that a negative result can be relied upon.
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