年度禁用物质审查第17版-人类运动药物检测的分析方法2023/2024。

IF 2.6 3区 医学 Q2 BIOCHEMICAL RESEARCH METHODS
Mario Thevis, Tiia Kuuranne, Hans Geyer
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引用次数: 0

摘要

第17期关于人类运动药物测试分析方法的禁用物质年度审查致力于2023年10月至2024年9月期间发表的文献。与前几年一样,本届年会的重点将放在新的或增强的人类兴奋剂控制分析方法上,以及对感兴趣的化合物的代谢和消除的研究,这是全球反兴奋剂任务的核心(但不是唯一的)基石。在世界反兴奋剂机构2024年禁用清单的背景下,审查和讨论过去12个月内发布的关于已确定的兴奋剂制剂以及新的潜在相关物质的新信息。因此,分析的挑战,特别是关于不断增长的目标化合物和潜在的相关药物类别,以及最大限度的分析回顾性的紧迫性(和后果),是主题化和背景化的。合成代谢药物、多肽激素和基因兴奋剂检测策略的研究被确定为本研究期间反兴奋剂研究的核心领域。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Annual Banned-Substance Review 17th Edition-Analytical Approaches in Human Sports Drug Testing 2023/2024.

The 17th edition of the annual banned-substance review on analytical approaches in human sports drug testing is dedicated to literature published between October 2023 and September 2024. As in previous years, focus is put particularly on new or enhanced analytical options in human doping controls as well as investigations into the metabolism and elimination of compounds of interest, which represent central (while not exclusive) cornerstones of the global anti-doping mission. New information published within the past 12 months on established doping agents as well as new potentially relevant substances are reviewed and discussed in the context of the World Anti-Doping Agency's 2024 Prohibited List. Thereby, analytical challenges, especially with regard to the continuously growing number of target compounds and potentially relevant drug classes as well as the exigency (and consequences) of utmost analytical retrospectivity, are thematized and contextualized. Investigations especially into anabolic agents, peptide hormones, and strategies for the detection of gene doping were identified as core areas of anti-doping research in the reviewed period.

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来源期刊
Drug Testing and Analysis
Drug Testing and Analysis BIOCHEMICAL RESEARCH METHODS-CHEMISTRY, ANALYTICAL
CiteScore
5.90
自引率
24.10%
发文量
191
审稿时长
2.3 months
期刊介绍: As the incidence of drugs escalates in 21st century living, their detection and analysis have become increasingly important. Sport, the workplace, crime investigation, homeland security, the pharmaceutical industry and the environment are just some of the high profile arenas in which analytical testing has provided an important investigative tool for uncovering the presence of extraneous substances. In addition to the usual publishing fare of primary research articles, case reports and letters, Drug Testing and Analysis offers a unique combination of; ‘How to’ material such as ‘Tutorials’ and ‘Reviews’, Speculative pieces (‘Commentaries’ and ‘Perspectives'', providing a broader scientific and social context to the aspects of analytical testing), ‘Annual banned substance reviews’ (delivering a critical evaluation of the methods used in the characterization of established and newly outlawed compounds). Rather than focus on the application of a single technique, Drug Testing and Analysis employs a unique multidisciplinary approach to the field of controversial compound determination. Papers discussing chromatography, mass spectrometry, immunological approaches, 1D/2D gel electrophoresis, to name just a few select methods, are welcomed where their application is related to any of the six key topics listed below.
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