门脉性肺动脉高压诊断和治疗中未满足的需求：我们达到了多少程度？

IF 12.9 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Hepatology Pub Date : 2024-12-26 DOI:10.1097/hep.0000000000001218

Michael J. Krowka, Hilary M. DuBrock, Sarah Raevens, Michael B. Fallon

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引用次数: 0

摘要

门脉高压（POPH）是肺动脉高压的一种形式，发生于门脉高压。肺血流动力学和右心功能是诊断和治疗POPH时需要考虑的关键因素。医学治疗结合肝移植为POPH“治愈”提供了一个独特的机会，然而移植风险可能很大，因为它与POPH的严重程度有关。除了最近的POPH实践指南外，可以建议继续努力提高我们对预后因素的理解，研究新的医学治疗方法，并改善POPH的结果。在此，我们确定了具体的“未满足的需求”，重点是扩大和补充目前的POPH实践指南。

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Unmet needs in diagnosis and management of portopulmonary hypertension: How far have we reached?

Portopulmonary hypertension (POPH), a form of pulmonary artery hypertension, occurs because of portal hypertension. Pulmonary hemodynamics and right heart function are key entities that are considered when diagnosing and treating POPH. Medical management, combined with liver transplantation, offers a unique opportunity of POPH “cure,” however transplant risk can be significant as it relates to the severity of POPH. In addition to recent POPH practice guidelines, continued efforts can be suggested to improve our understanding of prognostic factors, investigate newer medical treatments, and improve outcomes of POPH. Herein, we identify specific “unmet needs” that focus on expanding and complementing current POPH practice guidelines.

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来源期刊

Hepatology 医学-胃肠肝病学

CiteScore

27.50

自引率

3.70%

发文量

609

审稿时长

1 months

期刊介绍： HEPATOLOGY is recognized as the leading publication in the field of liver disease. It features original, peer-reviewed articles covering various aspects of liver structure, function, and disease. The journal's distinguished Editorial Board carefully selects the best articles each month, focusing on topics including immunology, chronic hepatitis, viral hepatitis, cirrhosis, genetic and metabolic liver diseases, liver cancer, and drug metabolism.