接种mRNA后，SLE B细胞绕道滤泡外

IF 27.7 1区医学 Q1 IMMUNOLOGY

Nature Immunology Pub Date : 2024-12-27 DOI:10.1038/s41590-024-02035-0

Sokratis A. Apostolidis, Michela Locci

引用次数: 0

摘要

系统性红斑狼疮（SLE）是一种自身免疫性疾病，具有相当大的临床异质性和多种治疗选择。现在的一项研究表明，滤泡外B细胞的增加和抗baff治疗与对COVID-19疫苗的不良反应有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

SLE B cells take an extrafollicular detour after mRNA vaccination

查看原文本刊更多论文

SLE B cells take an extrafollicular detour after mRNA vaccination

Systemic lupus erythematosus (SLE) is an autoimmune disease with considerable clinical heterogeneity and diverse treatment options. A study now shows that heightened extrafollicular B cells and anti-BAFF therapy are linked to inferior responses to COVID-19 vaccines.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Nature Immunology 医学-免疫学

CiteScore

40.00

自引率

2.30%

发文量

248

审稿时长

4-8 weeks

期刊介绍： Nature Immunology is a monthly journal that publishes the highest quality research in all areas of immunology. The editorial decisions are made by a team of full-time professional editors. The journal prioritizes work that provides translational and/or fundamental insight into the workings of the immune system. It covers a wide range of topics including innate immunity and inflammation, development, immune receptors, signaling and apoptosis, antigen presentation, gene regulation and recombination, cellular and systemic immunity, vaccines, immune tolerance, autoimmunity, tumor immunology, and microbial immunopathology. In addition to publishing significant original research, Nature Immunology also includes comments, News and Views, research highlights, matters arising from readers, and reviews of the literature. The journal serves as a major conduit of top-quality information for the immunology community.