白内障眼生物特征测量的变异性和相关性评估。

IF 3.1 3区医学 Q2 ONCOLOGY

Photodiagnosis and Photodynamic Therapy Pub Date : 2025-02-01 DOI:10.1016/j.pdpdt.2024.104453

Jian-Feng Zhao, Chen Yang, Jie Zhou, Hai-Yan Zhang, Yu Geng

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引用次数: 0

摘要

目的：评估白内障眼生物特征参数的变异性和相关性，并探讨其与年龄和性别的关系。方法：采用配备低相干反射技术的光学生物计，对无视网膜病变的7,458只眼的生物特征数据进行回顾性分析。使用Pearson相关系数(r)来评估年龄、性别和各种眼部参数之间的关系，包括眼轴长度（AL）、前房深度（ACD）、晶状体厚度（LT）、角膜中央厚度（CCT）、角膜屈光度（Km）和白对白（WTW）测量。结果：平均AL为23.82±1.83 mm （SD）。在研究队列中，8.0%（593只眼）为短AL (AL≤22 mm), 60.5%（4520只眼）为正常AL (22 mm < AL≤24 mm), 21.2%（1579只眼）为长AL (24 mm < AL≤26 mm), 10.3%（766只眼）为AL （> 26 mm）。队列平均年龄为64.18±14.95岁（范围：18 ~ 98岁），男性平均56.53±13.88岁，女性平均72.19±11.41岁。ACD、LT、Km、CCT、WTW和角kappa的平均值随年龄和性别而变化。与女性相比，男性AL更长，ACD更深，LT更厚，WTW更大，Km更低（P < 0.05）。虽然男性表现出更大的前段长度（ASL），但差异无统计学意义（P < 0.05）。短AL组和长AL组的ACD与AL无显著相关，而正常AL组和长AL组的ACD与AL呈正相关。此外，LT与AL在正常AL组呈负相关，而在长AL组呈正相关。结论：女性白内障患者的发病年龄大于男性。眼生物特征参数，包括ACD、LT、CCT、Km和（WTW）测量，受年龄和性别的影响。透镜厚度是影响ACD的主要因素，CCT、Km和WTW也起着重要作用。此外，AL和LT之间存在负相关，其差异取决于AL的分类。

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Assessment of the variability and correlation of biometric measurements in eyes with cataracts

Purpose

To assess the variability and correlation of ocular biometric parameters in eyes with cataracts and examine their association with age and gender.

Methods

A retrospective analysis was performed on biometric data from 7,458 eyes without retinal pathologies, using an optical biometer equipped with low-coherence reflectometry technology. Pearson's correlation coefficients (r) were used to evaluate the relationships between age, gender, and various ocular parameters, including axial length (AL), anterior chamber depth (ACD), lens thickness (LT), central corneal thickness (CCT), corneal refractive power (Km), and white-to-white (WTW) measurement.

Results

The mean AL was 23.82 ± 1.83 mm (SD). Among the study cohort, 8.0 % (593 eyes) were categorized as having short AL (AL ≤ 22 mm), 60.5 % (4,520 eyes) as having normal AL (22 mm < AL ≤ 24 mm), 21.2 % (1,579 eyes) as having long AL (24 mm < AL ≤ 26 mm), and 10.3 % (766 eyes) as having a AL (> 26 mm). The mean age of the cohort was 64.18 ± 14.95 years (range: 18 - 98 years), with males averaging 56.53 ± 13.88 years and females averaging 72.19 ± 11.41 years. Mean values for ACD, LT, Km, CCT, WTW, and angle kappa were found to vary with both age and gender. Males demonstrated significantly longer AL, deeper ACD, thicker LT, larger WTW, and lower Km compared to females (P < 0.05). Although males exhibited a greater anterior segment length (ASL), this difference did not reach statistical significance (P > 0.05). No significant correlation was found between ACD and AL in the short and long AL groups, while a positive correlation was observed in the normal and long AL groups. Additionally, LT demonstrated a negative correlation with AL in the normal AL group but a positive correlation in the long AL group.

Conclusions

Cataracts develop at a greater age in female patients than in males. Ocular biometric parameters, including ACD, LT, CCT, Km, and (WTW) measurement, are influenced by age and gender. Lens thickness is the primary factor affecting ACD, though CCT, Km, and WTW also play significant roles. Furthermore, a negative correlation between AL and LT was identified, with variations depending on AL classification.

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来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.