儿童恶性生殖细胞肿瘤伴广泛腔房肿瘤血栓的成功治疗结果作为肿瘤急症。

IF 0.9 4区医学 Q4 HEMATOLOGY

Journal of Pediatric Hematology/Oncology Pub Date : 2025-01-01 Epub Date: 2024-12-16 DOI:10.1097/MPH.0000000000002978

Sai Shiva G, Prasanth Vr, Rajani Lilly Cheriyan, Ajay Sankar, Manjusha Nair, Binitha Rajeswari, Guruprasad Cs, Kalasekhar Vs, Baiju S Dharan, Priyakumari Thankamony

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引用次数: 0

摘要

背景：小儿生殖细胞肿瘤（GCT）合并广泛的腔室-心房肿瘤血栓作为肿瘤急症是极为罕见的。观察：我们报告了一例13个月大的女骶尾骨GCT患儿，伴有下腔静脉（IVC）和右心房血栓，表现为无血管和呼吸窘迫。由于化疗开始后症状加重，于第9天急诊行右心房及下腔静脉远端肿瘤血栓清除术。她的症状有所改善，在计划化疗后，可以进行肿瘤切除和尾骨切除术。由于硬化，下腔静脉血栓仍不能手术。治疗12个月后，她仍然没有复发。

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Successful Treatment Outcome of a Pediatric Malignant Germ Cell Tumor With an Extensive Cavo-atrial Tumor Thrombus Presenting as an Oncological Emergency.

Background: Pediatric germ cell tumor (GCT) with extensive cavo-atrial tumor thrombus presenting as an oncologic emergency is extremely rare.

Observation: A 13-month-old female child with sacrococcygeal GCT having inferior vena cava (IVC) and right atrial thrombus presenting with anasarca and respiratory distress is reported. Because of worsening symptoms post initiation of chemotherapy, tumor thrombus debulking from the right atrium and distal end of IVC was performed on day 9 on an emergency basis. Her symptoms improved, and after planned chemotherapy, tumor excision with coccygectomy could be done. The IVC thrombus remained inoperable due to sclerosis. She remains recurrent-free now 12 months post therapy.

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来源期刊

Journal of Pediatric Hematology/Oncology 医学-小儿科

CiteScore

1.90

自引率

8.30%

发文量

415

审稿时长

2.5 months

期刊介绍： Journal of Pediatric Hematology/Oncology (JPHO) reports on major advances in the diagnosis and treatment of cancer and blood diseases in children. The journal publishes original research, commentaries, historical insights, and clinical and laboratory observations.