巴勒斯坦魔芋的植物化学和生物学研究进展。

IF 1.6 3区化学 Q3 CHEMISTRY, APPLIED

Natural Product Research Pub Date : 2026-05-03 Epub Date: 2024-12-16 DOI:10.1080/14786419.2024.2443486

Ghassan Albarghouti , Baydaa’ Habash

{"title":"巴勒斯坦魔芋的植物化学和生物学研究进展。","authors":"Ghassan Albarghouti , Baydaa’ Habash","doi":"10.1080/14786419.2024.2443486","DOIUrl":null,"url":null,"abstract":"<div><div><em>Arum palaestinum</em> is a wild edible, parietal, unisexual, perennial plant that grows in various parts of the Middle East, and frequently used in traditional Arabic Palestinian herbal medicine. The present review summarises information concerning <em>Arum palaestinum</em> including background information, historical records, phytochemical components, and biological activity which represents an important tool for further research studies. <em>Arum palaestinum</em> is thought to contain a wealth of rich bioactive compounds, such as terpinoids, polyphenols, flavonoids, and alkaloids. Long-term research on these compounds has demonstrated antioxidant, antibacterial, anti-inflammatory, and anticancer activities. Its aerial parts yielded the identification of over 180 chemicals, whereas its flowering part’s GC/MS study revealed the presence of twelve compounds. Its leaf extracts demonstrated toxicity against various cancer cell lines. Extracts from its flowers demonstrated potent anti-inflammatory and dose-dependent cytotoxic effects. The potential of GZ17-6.02, a promising combinatorial drug made from plant components, for clinical cancer treatment is still being investigated.</div></div>","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":"40 9","pages":"Pages 2578-2595"},"PeriodicalIF":1.6000,"publicationDate":"2026-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A review on Arum palaestinum: phytochemical and biological aspects\",\"authors\":\"Ghassan Albarghouti , Baydaa’ Habash\",\"doi\":\"10.1080/14786419.2024.2443486\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div><em>Arum palaestinum</em> is a wild edible, parietal, unisexual, perennial plant that grows in various parts of the Middle East, and frequently used in traditional Arabic Palestinian herbal medicine. The present review summarises information concerning <em>Arum palaestinum</em> including background information, historical records, phytochemical components, and biological activity which represents an important tool for further research studies. <em>Arum palaestinum</em> is thought to contain a wealth of rich bioactive compounds, such as terpinoids, polyphenols, flavonoids, and alkaloids. Long-term research on these compounds has demonstrated antioxidant, antibacterial, anti-inflammatory, and anticancer activities. Its aerial parts yielded the identification of over 180 chemicals, whereas its flowering part’s GC/MS study revealed the presence of twelve compounds. Its leaf extracts demonstrated toxicity against various cancer cell lines. Extracts from its flowers demonstrated potent anti-inflammatory and dose-dependent cytotoxic effects. The potential of GZ17-6.02, a promising combinatorial drug made from plant components, for clinical cancer treatment is still being investigated.</div></div>\",\"PeriodicalId\":18990,\"journal\":{\"name\":\"Natural Product Research\",\"volume\":\"40 9\",\"pages\":\"Pages 2578-2595\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2026-05-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Natural Product Research\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/org/science/article/pii/S1478641924009793\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/12/16 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural Product Research","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1478641924009793","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/12/16 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}

引用次数: 0

摘要

巴勒斯坦魔芋是一种野生可食、顶生、单性、多年生植物，生长在中东的许多地方，经常用于传统的阿拉伯巴勒斯坦草药。本文对巴勒斯坦魔芋的背景资料、历史记载、植物化学成分、生物活性等方面的研究进行了综述，为进一步研究提供了重要的工具。巴勒斯坦魔芋被认为含有丰富的生物活性化合物，如萜类化合物、多酚、类黄酮和生物碱。长期研究表明，这些化合物具有抗氧化、抗菌、抗炎和抗癌活性。其地上部分鉴定出超过180种化学物质，而其开花部分的GC/MS研究显示存在12种化合物。其叶提取物显示出对多种癌细胞系的毒性。其花提取物显示出有效的抗炎和剂量依赖的细胞毒性作用。GZ17-6.02是一种由植物成分制成的有前景的组合药物，用于临床癌症治疗的潜力仍在研究中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

A review on Arum palaestinum: phytochemical and biological aspects

Arum palaestinum is a wild edible, parietal, unisexual, perennial plant that grows in various parts of the Middle East, and frequently used in traditional Arabic Palestinian herbal medicine. The present review summarises information concerning Arum palaestinum including background information, historical records, phytochemical components, and biological activity which represents an important tool for further research studies. Arum palaestinum is thought to contain a wealth of rich bioactive compounds, such as terpinoids, polyphenols, flavonoids, and alkaloids. Long-term research on these compounds has demonstrated antioxidant, antibacterial, anti-inflammatory, and anticancer activities. Its aerial parts yielded the identification of over 180 chemicals, whereas its flowering part’s GC/MS study revealed the presence of twelve compounds. Its leaf extracts demonstrated toxicity against various cancer cell lines. Extracts from its flowers demonstrated potent anti-inflammatory and dose-dependent cytotoxic effects. The potential of GZ17-6.02, a promising combinatorial drug made from plant components, for clinical cancer treatment is still being investigated.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Natural Product Research 化学-医药化学

CiteScore

5.10

自引率

9.10%

发文量

605

审稿时长

2.1 months

期刊介绍： The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds. The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal. Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section. All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.