澳大利亚维多利亚州阿片类药物处方患病率和起始率:阿片类药物政策变化期间(2017-2022)初级保健数据的见解

IF 2.6 4区 医学 Q2 PHARMACOLOGY & PHARMACY
Zeynep Balikci, Ulyana Kondratova, Louisa Picco, Suzanne Nielsen, Ting Xia
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引用次数: 0

摘要

背景:阿片类药物被广泛用于急性、慢性和癌性疼痛。在澳大利亚,阿片类药物处方率仍然很高。目的:本研究旨在通过人口统计学特征记录2017年至2022年澳大利亚维多利亚州初级保健阿片类药物处方模式。方法:本研究采用回顾性描述性分析,检查来自人群水平分析和报告全科分析平台的处方数据。我们检查了不同人口因素(如年龄、性别、社会经济地位(SES)和地理位置)的每月阿片类药物处方和起始率。泊松回归用于计算阿片类药物起始发生率随时间的比率,调整年龄、性别和社会经济地位。结果:2017 - 2022年,他他多的处方增加了263%,而其他阿片类药物的处方率下降。女性占阿片类药物处方的53%,但男性的起始率更高。除15-24岁年龄组增加了69%外,大多数人口的入会率都有所下降。社会经济弱势群体和地区/偏远人群的处方率较高,但随着时间的推移显着下降。结论:本研究对初级卫生机构的处方趋势提供了有价值的见解。研究结果表明,需要有针对性的干预措施来解决社会经济和区域差异,以确保在不同人群中高质量地使用阿片类药物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Opioid prescribing prevalence and initiation rates in Victoria, Australia: insights from primary care data during a period of opioid policy changes (2017-2022).

Background: Opioid medications are widely prescribed for acute, chronic and cancer pain. In Australia, opioid prescribing rates remain high.

Aim: This study aimed to document patterns of primary care opioid prescribing from 2017 to 2022 by demographic characteristics in Victoria, Australia.

Method: This study was a retrospective descriptive analysis, examining prescribing data sourced from the population level analysis and reporting general practice analytics platform. We examined monthly opioid prescription and initiation rates across diverse demographic factors such as age, gender, socioeconomic status (SES), and geographical location. Poisson regression was used to calculate rate ratios for the incidence of opioid initiation over time, adjusting for age, gender, and SES.

Results: Between 2017 and 2022, tapentadol prescriptions increased by 263%, while prescription rates for other opioids declined. Females accounted for 53% of opioid prescriptions, but males had higher initiation rates. Initiation rates declined across most demographics, except for the 15-24 age group, which experienced a 69% increase. Socioeconomically disadvantaged and regional/remote populations showed higher prescribing rates but significant declines over time.

Conclusion: This study contributes valuable insights into the prescribing trends in primary health settings. The findings suggest targeted interventions to address socioeconomic and regional disparities are needed, to ensure the quality use of opioids across diverse populations.

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来源期刊
CiteScore
4.10
自引率
8.30%
发文量
131
审稿时长
4-8 weeks
期刊介绍: The International Journal of Clinical Pharmacy (IJCP) offers a platform for articles on research in Clinical Pharmacy, Pharmaceutical Care and related practice-oriented subjects in the pharmaceutical sciences. IJCP is a bi-monthly, international, peer-reviewed journal that publishes original research data, new ideas and discussions on pharmacotherapy and outcome research, clinical pharmacy, pharmacoepidemiology, pharmacoeconomics, the clinical use of medicines, medical devices and laboratory tests, information on medicines and medical devices information, pharmacy services research, medication management, other clinical aspects of pharmacy. IJCP publishes original Research articles, Review articles , Short research reports, Commentaries, book reviews, and Letters to the Editor. International Journal of Clinical Pharmacy is affiliated with the European Society of Clinical Pharmacy (ESCP). ESCP promotes practice and research in Clinical Pharmacy, especially in Europe. The general aim of the society is to advance education, practice and research in Clinical Pharmacy . Until 2010 the journal was called Pharmacy World & Science.
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