免疫组织化学在妇科肿瘤中的应用：专家综述。

IF 1.2 Q3 OBSTETRICS & GYNECOLOGY

Gynecologic Oncology Reports Pub Date : 2024-12-01 DOI:10.1016/j.gore.2024.101550

Arielle H. Katcher , Michelle P. Greenman , Sudarshana Roychoudhury , Gary L. Goldberg

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引用次数: 0

摘要

在过去的30年里，免疫组织化学（IHC）和分子病理学的使用已经被广泛采用，并有助于精确诊断妇科肿瘤。虽然许多肿瘤可以通过常规苏木精和伊红染色玻片的组织学外观来诊断，但免疫结构的使用已经极大地改变了实践，导致对妇科肿瘤的更好理解和分型。这种肿瘤的详细分类有助于靶向治疗的实施和发展。可用的免疫组化染色剂及其应用继续快速发展。我们的综述旨在提供IHC在妇科肿瘤中应用的最新信息。我们还将讨论基于免疫组化的个性化首选治疗方案的基本原理。

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Utilization of immunohistochemistry in gynecologic tumors: An expert review

The use of immunohistochemistry (IHC) and molecular pathology has been widely adopted over the past 3 decades and has aided in the precision of diagnosing gynecologic tumors. While many tumors can be diagnosed by histologic appearance on routine hematoxylin and eosin stained slides, the use of IHC has dramatically changed practice, leading to a better understanding and subtyping of gynecologic tumors. This detailed classification of tumors has aided in the implementation and development of targeted therapies. Available IHC stains and their applications continue to rapidly evolve. Our review aims to provide updated information on the use of IHC in gynecologic tumors. We will also address the rationale for preferred therapeutic regimens that are personalized based on IHC.

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来源期刊

Gynecologic Oncology Reports OBSTETRICS & GYNECOLOGY-

CiteScore

2.00

自引率

0.00%

发文量

183

审稿时长

41 days

期刊介绍： Gynecologic Oncology Reports is an online-only, open access journal devoted to the rapid publication of narrative review articles, survey articles, case reports, case series, letters to the editor regarding previously published manuscripts and other short communications in the field of gynecologic oncology. The journal will consider papers that concern tumors of the female reproductive tract, with originality, quality, and clarity the chief criteria of acceptance.